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Merck
CN

PHR1083

奥克立林

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

2-氰基-3,3-二苯基-2-丙烯酸-2-乙己酯, OC

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关于此项目

线性分子式:
(C6H5)2C=C(CN)CO2CH2CH(C2H5)(CH2)3CH3
化学文摘社编号:
分子量:
361.48
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
228-250-8
MDL number:
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Quality Level

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1477411

API family

octocrylene

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

refractive index

n20/D 1.567 (lit.)

bp

218 °C/1.5 mmHg (lit.)

mp

−10 °C (lit.)

density

1.051 g/mL at 25 °C (lit.)

application(s)

environmental
pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

CCCCC(CC)COC(=O)\C(C#N)=C(/c1ccccc1)c2ccccc2

InChI

1S/C24H27NO2/c1-3-5-12-19(4-2)18-27-24(26)22(17-25)23(20-13-8-6-9-14-20)21-15-10-7-11-16-21/h6-11,13-16,19H,3-5,12,18H2,1-2H3

InChI key

FMJSMJQBSVNSBF-UHFFFAOYSA-N

General description

制药二级标准用于质量控制,为制药实验室和制造商提供了一种方便、经济的内部工作标准编制替代方案。

Application

奥克立林可用作药物参考标准品,通过色谱技术测定药物制剂中的分析物。
这些二级标准品是经过检验的认证标准物质(CRM)。它们适用于多种分析应用,包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他标定应用。

Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

Other Notes

要查看该材料的检验报告示例,请在下面的栏位中输入 LRAC0433。这只是一个示例证书,可能不是您收到的批次。
该认证标准物质(CRM)根据ISO 17034ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在分析证书上找到。


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signalword

Warning

存储类别

10 - Combustible liquids

flash_point_f

453.2 °F - closed cup

flash_point_c

234 °C - closed cup

pictograms

Health hazardEnvironment

Hazard Classifications

Aquatic Chronic 1 - Repr. 2



分析证书(COA)

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The difficulties for a photolabile drug in topical formulations: The case of diclofenac
Ioele G, et al.
International Journal of Pharmaceutics, 465(1-2), 284-290 (2014)
Lucie Duracher et al.
Photochemistry and photobiology, 85(6), 1459-1467 (2009-08-07)
Increasing legal requirements for risk assessment and efficacy testing in the dermo-cosmetic field have led to the development of alternative test methods. In this study, the porcine skin model was chosen to test the effect of irradiation on the penetration
Weihong Li et al.
Water research, 41(15), 3506-3512 (2007-06-29)
Four UV filters, benzophenone-3 (BP-3), 4-methylbenzylidence camphor (4-MBC), ethylhexyl methoxycinnamate (EHMC), and octocrylene (OC), have been examined along the different units of a wastewater reclamation plant (WWRP) located in Tianjin, North China. The analytical procedure included solid-phase extraction and gas



全球贸易项目编号

货号GTIN
PHR1083-10G04061835232895
PHR1083-1G04061837883972