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Merck
CN

PHR1434

焦亚硫酸钠

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

偏亚硫酸氢钠, 偏二亚硫酸钠, 焦亚硫酸钠

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关于此项目

线性分子式:
Na2S2O5
化学文摘社编号:
分子量:
190.11
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
231-673-0
MDL number:
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产品名称

焦亚硫酸钠, Pharmaceutical Secondary Standard; Certified Reference Material

InChI

1S/2Na.H2O5S2/c;;1-6(2)7(3,4)5/h;;(H,1,2)(H,3,4,5)/q2*+1;/p-2

InChI key

HRZFUMHJMZEROT-UHFFFAOYSA-L

SMILES string

[Na+].[Na+].[O-]S(=O)S([O-])(=O)=O

grade

certified reference material
pharmaceutical secondary standard

agency

traceable to USP 1614396

API family

sodium metabisulfite

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

>300 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

Quality Level

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Analysis Note

这些二级标准品可追溯至USP、EP和BP一级标准品。

Application

焦亚硫酸钠可作为药物标准品,用于通过电流测量技术对药物制剂中的分析物进行定量。
这些二级标准品是合格的认证标准物质(CRM)。它们适用于多种分析应用,包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他校准需求。

General description

用于质量控制的经认证的药物二级标准为制药实验室和制造商提供了一种方便且具有成本效益的药典主要标准替代品。焦亚硫酸钠是一种硫化剂,广泛用作药物制剂以及各种食品和饮料中的抗氧化剂,防腐剂和褐变抑制剂。

Other Notes

想要查看本品的检验报告示例,请在下框中输入LRAC2953。这只是一个示例证书,可能与您收到的批次不符。
该认证标准物质(CRM)根据ISO 17034ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在检验报告上找到。

pictograms

CorrosionExclamation mark

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1

supp_hazards

存储类别

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Amperometric quantification of sodium metabisulfite in pharmaceutical formulations utilizing tetraruthenated porphyrin film modified electrodes and batch injection analysis.
Quintino MSM, et al.
Talanta, 68(4), 1281-1286 (2006)
Juan García-Gavín et al.
Contact dermatitis, 67(5), 260-269 (2012-10-09)
Sulfites, preservatives and antioxidants used in the cosmetic, pharmaceutical and food industry are contact allergens whose relevance seems to be difficult to establish. To perform a retrospective study on patients patch tested with a sulfite. Materials and methods. Between 1990
Natalia Mosconi et al.
ChemMedChem, 9(6), 1211-1220 (2014-05-09)
We report the synthesis, characterization, antibacterial and antifungal activities, phytotoxicity, and genotoxicity of two new complexes of silver(I) with sulfachloropyridazine (SCP), one of which is heteroleptic with SCP and SCN(-) ligands (Ag-SCP-SCN), the other of which is homoleptic (Ag-SCP); furthermore
Ping Chu et al.
PLoS pathogens, 10(10), e1004439-e1004439 (2014-10-24)
Francisella tularensis causes the disease tularemia. Human pulmonary exposure to the most virulent form, F. tularensis subsp. tularensis (Ftt), leads to high morbidity and mortality, resulting in this bacterium being classified as a potential biothreat agent. However, a closely-related species
Sarah Bradbury et al.
Addiction biology, 19(5), 874-884 (2013-06-15)
The current study aimed to elucidate the role of pharmacokinetic (PK) parameters and neurotransmitter efflux in explaining variability in (±) 3, 4-methylenedioxymethamphetamine (MDMA) self-administration in rats. PK profiles of MDMA and its major metabolites were determined after the administration of

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