Merck
CN
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文件

PHR1798

Supelco

左旋咪唑

Pharmaceutical Secondary Standard; Certified Reference Material

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别名:
(−)-四咪唑 盐酸盐, L（−）- 2，3，5，6-四氢-6-苯基咪唑并[2，1-b]噻唑 盐酸盐, 左旋咪唑 盐酸盐, （S）-（−）-6-苯基-2，3，5，6-四氢咪唑并[2，1-b]噻唑 盐酸盐
经验公式（希尔记法）:
C11H12N2S · HCl
CAS号:
16595-80-5
分子量:
240.75
Beilstein:
4358988
EC 号:
240-654-6
MDL编号:
MFCD00012675
NACRES:
NA.24

等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to BP 212
traceable to Ph. Eur. L0380000
traceable to USP 1359302

API family

levamisole

CofA

current certificate can be downloaded

包装

pkg of 250 mg

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

228-230 °C

application(s)

pharmaceutical (small molecule)

格式

neat

储存温度

2-30°C

SMILES string

Cl.C1CN2C[C@@H](N=C2S1)c3ccccc3

InChI

1S/C11H12N2S.ClH/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10;/h1-5,10H,6-8H2;1H/t10-;/m1./s1

InChI key

LAZPBGZRMVRFKY-HNCPQSOCSA-N

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相关类别

一般描述

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

应用

Levamisole Hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by potentiometric sensing, spectrometric and atomic absorption spectroscopy methods.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生化/生理作用

根据一些可控因素，同时显示免疫刺激和免疫抑制作用。治疗蛔虫病（钩虫感染）非常有效。可用于结肠直肠癌的化疗，可能是由于其刺激IL-1 产生和巨噬细胞的直接激活。

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAC3172 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

推荐产品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

象形图

Skull and crossbones
GHS06

警示用语：

Danger

危险声明

H301

预防措施声明

P301 + P310 + P330

危险分类

Acute Tox. 3 Oral

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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Indirect determination of levamisole by AAS and precipitation in a continuous-flow assembly
Ortiz SL, et al.
Microchemical Journal, Devoted to the Application of Microtechniques in All Branches of Science, 48(1), 112-117 (1993)
Davide Caprini et al.
Advanced biology, 5(9), e2100927-e2100927 (2021-08-24)
AWC olfactory neurons are fundamental for chemotaxis toward volatile attractants in Caenorhabditis elegans. Here, it is shown that AWCON responds not only to chemicals but also to mechanical stimuli caused by fluid flow changes in a microfluidic device. The dynamics
Potentiometric sensing of levamisole hydrochloride based on molecularly imprinted polymer
Sadeghi S, et al.
Sensors and Actuators B, Chemical, 122(1), 158-164 (2007)
Sreeparna Pradhan et al.
Current biology : CB, 29(17), 2867-2879 (2019-08-20)
Foraging strategies should be tuned to the expected distribution of resources in the environment. Tuning can occur over generations and lead to genetic differences in innate foraging behavior or over shorter timescales within an individual's lifespan. Both genetically encoded and
Jote T Bulcha et al.
Cell reports, 26(2), 460-468 (2019-01-10)
Biological systems must possess mechanisms that prevent inappropriate responses to spurious environmental inputs. Caenorhabditis elegans has two breakdown pathways for the short-chain fatty acid propionate: a canonical, vitamin B12-dependent pathway and a propionate shunt that is used when vitamin B12
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