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Merck
CN

PHR1908

乙酰唑胺

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

乙酰唑胺, 5-乙酰胺基-1,3,4-噻二唑-2-磺酰胺, N-(5-[氨基磺酰基]-1,3,4-噻二唑-2-基)乙酰胺, N-(5-氨磺酰基-1,3,4-噻二唑-2-基)乙酰胺

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经验公式(希尔记法):
C4H6N4O3S2
化学文摘社编号:
分子量:
222.25
UNSPSC Code:
41116107
NACRES:
NA.24
EC Number:
200-440-5
MDL number:
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InChI key

BZKPWHYZMXOIDC-UHFFFAOYSA-N

InChI

1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)

SMILES string

CC(=O)Nc1nnc(s1)S(N)(=O)=O

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. A0100000, traceable to USP 1005004

API family

acetazolamide

CofA

current certificate can be downloaded

packaging

pkg of 5 g

application(s)

pharmaceutical

format

neat

storage temp.

2-30°C

Quality Level

Gene Information

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Application

碳酸酐酶抑制剂;增加脑血流量。

Biochem/physiol Actions

通过与水通道蛋白相互作用抑制膜的水渗透性

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAB0911 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

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RP-HPLC method development and validation for the estimation of acetazolamide in bulk drug and formulations with forced degradation studies.
Manchanda S.
Der Pharmacia Lettre, 8, 338-347 (2016)
Acetazolamide improves central sleep apnea in heart failure: a double-blind, prospective study.
Javaheri S.
American Journal of Respiratory and Critical Care Medicine, 173(2), 234-237 (2006)
Acetazolamide.
Parasrampuria J.
Anal. Profiles Drug Subst., 22, 1-32 (1993)

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