PHR1919
氯唑沙宗
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
Chlorzoxazone, CLZ, 5-Chloro-2(3H)-benzoxazolone, 5-Chloro-2-hydroxybenzoxazole
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关于此项目
经验公式（希尔记法）:
C7H4ClNO2
化学文摘社编号:
分子量:
169.57
UNSPSC Code:
41116107
NACRES:
NA.24
EC Number:
222-649-0
MDL number:
产品名称
氯唑沙宗, Pharmaceutical Secondary Standard; Certified Reference Material
InChI key
TZFWDZFKRBELIQ-UHFFFAOYSA-N
InChI
1S/C7H4ClNO2/c8-4-1-2-6-5(3-4)9-7(10)11-6/h1-3H,(H,9,10)
SMILES string
Clc1ccc2OC(=O)Nc2c1
grade
certified reference material
pharmaceutical secondary standard
agency
traceable to USP 1130505
API family
chlorzoxazone
CofA
current certificate can be downloaded
packaging
pkg of 500 mg
mp
191-192 °C (lit.)
application(s)
pharmaceutical
format
neat
storage temp.
2-30°C
Quality Level
Gene Information
human ... KCNN4(3783)
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Analysis Note
These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
Application
Chlorzoxazone may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography technique, spectrophotometry and fluorescence spectroscopy.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Biochem/physiol Actions
Chlorzoxazone is a skeletal muscle relaxant.
General description
Chlorzoxazone is a centrally active muscle relaxant used to treat painful muscle spasms linked to musculoskeletal disorders, such as fibrositis, bursitis, myositis, spondylitis, etc.
Pharmaceutical secondary standard for application in quality control. Provides pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Pharmaceutical secondary standard for application in quality control. Provides pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAB0913 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Second derivative synchronous fluorescence spectroscopy for the simultaneous determination of chlorzoxazone and ibuprofen in pharmaceutical preparations and biological fluids
El-Enany N, et al.
International Journal of Biomedical Science : IJBS, 5(2), 136-136 (2009)
Development and validation of spectrophotometric methods for simultaneous estimation of tramadol hydrochloride and chlorzoxazone in tablet dosage form
Puranik M, et al.
Indian Journal of Pharmaceutical Sciences, 68(6), 737-737 (2006)
Simultaneous determination of aceclofenac, paracetamol, and chlorzoxazone by RP-HPLC in pharmaceutical dosage form
Shaikh KA and Devkhile AB
Journal of Chromatographic Science, 46(7), 649-652 (2008)
Analytical Profiles of Drug Substances, 16(7), 119-144 (1987)
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