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Merck
CN

PHR8735

Supelco

R-Methotrexate

certified reference material, pharmaceutical secondary standard

别名:

(−)-Amethopterin, (2R)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]pentanedioic acid

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关于此项目

经验公式（希尔记法）:
C20H22N8O5
化学文摘社编号:
51865-79-3
分子量:
454.44
MDL编号:
MFCD00006710
UNSPSC代码:
41116107

主要文件

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等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to USP (Catalog No. 1413988)

API类

methotrexate

CofA

current certificate can be downloaded

包装

pkg of 25 mg

应用

pharmaceutical

SMILES字符串

O.CN(Cc1cnc2nc(N)nc(N)c2n1)c3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O

InChI

1S/C20H22N8O5.H2O/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30;/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30)(H,32,33)(H4,21,22,23,26,27);1H2

InChI key

FPJYMUQSRFJSEW-UHFFFAOYSA-N

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相关类别

一般描述

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析说明

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA6959(changes by product) in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

象形图

Skull and crossbonesHealth hazard
GHS06,GHS08

警示用语：

Danger

危险分类

Acute Tox. 3 Oral - Muta. 2 - Repr. 1B - STOT RE 1

靶器官

Liver,Bone marrow

储存分类代码

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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