T5428
四甲基罗丹明甲酯高氯酸盐
≥95% purity, powder
别名:
TMRM
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关于此项目
线性分子式:
C25H25N2O3 · ClO4
化学文摘社编号:
分子量:
500.93
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
MDL number:
Beilstein/REAXYS Number:
7162165
产品名称
四甲基罗丹明甲酯高氯酸盐, ≥95%
InChI
1S/C25H25N2O3.ClHO4/c1-26(2)16-10-12-20-22(14-16)30-23-15-17(27(3)4)11-13-21(23)24(20)18-8-6-7-9-19(18)25(28)29-5;2-1(3,4)5/h6-15H,1-5H3;(H,2,3,4,5)/q+1;/p-1
SMILES string
[O-]Cl(=O)(=O)=O.COC(=O)c1ccccc1C2=C3C=C\C(C=C3Oc4cc(ccc24)N(C)C)=[N+](\C)C
InChI key
PFYWPQMAWCYNGW-UHFFFAOYSA-M
assay
≥95%
form
powder
composition
Carbon: 57.5-62.4%
Nitrogen: 5.3-5.9%
technique(s)
titration: suitable
color
dark green
solubility
methanol: 5 mg/mL, clear
εmax
>95000 at 546-552 nm in methanol
fluorescence
λem 573 nm in methanol
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
2-8°C
Quality Level
General description
四甲基罗丹明甲酯高氯酸盐（TMRM）是一种膜渗透、阳离子荧光染料，可以标记线粒体和标记胚胎干细胞/诱导多能干细胞来源的心肌细胞。它可用于分离成熟的心肌细胞。
Application
四甲基罗丹明甲酯高氯酸盐（TMRM）已用作检测线粒体膜电位的敏感探针。
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
Markus Hartl et al.
Molecular systems biology, 13(10), 949-949 (2017-10-25)
Histone deacetylases have central functions in regulating stress defenses and development in plants. However, the knowledge about the deacetylase functions is largely limited to histones, although these enzymes were found in diverse subcellular compartments. In this study, we determined the
Therapeutic Targeting of the Mitochondria Initiates Excessive Superoxide Production and Mitochondrial Depolarization Causing Decreased mtDNA Integrity
Kaytee L
PLoS ONE (2016)
Yuejiao Ma et al.
Journal of cell science, 132(15) (2019-07-11)
Mitochondrial remodelling is a central feature of stem cell differentiation. However, little is known about the regulatory mechanisms during these processes. Previously, we found that a pharmacological inhibitor of glycogen synthase kinase-3α and -3β, CHIR-99021, initiates human adipose stem cell
Emerging Trends in Cell and Gene Therapy null
Quantitative analysis of mitochondrial morphology and membrane potential in living cells using high-content imaging, machine learning, and morphological binning
Anthony P
Biochimica et Biophysica Acta (2015)
商品
Nitric oxide (NO) as a signal transporter in neurons, endothelial cells and in the immune system.
一氧化氮 (NO) 是神经元、内皮细胞和免疫系统中的信号转运分子。
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
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