InChI
1S/C10H8O3/c1-6-4-10(12)13-9-5-7(11)2-3-8(6)9/h2-5,11H,1H3
SMILES string
CC1=CC(=O)Oc2cc(O)ccc12
InChI key
HSHNITRMYYLLCV-UHFFFAOYSA-N
grade
pharmaceutical primary standard
API family
hymecromone
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
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存储类别
11 - Combustible Solids
wgk
WGK 2
Etty Osher et al.
Orphanet journal of rare diseases, 10, 45-45 (2015-04-22)
Late Onset Tay- Sachs disease (LOTS) is a rare neurodegenerative lysosomal storage disease which results from mutations in the gene encoding the α subunit (HEXA) of β-hexosaminidase enzyme (HexA). At the present time, no effective treatment exists for LOTS and
Ching-Chieh Weng et al.
Molecular cancer, 18(1), 96-96 (2019-05-22)
The TG-interacting factor 1 (TGIF1) gene, which encodes a nuclear transcriptional corepressor of the TGFβ1/Smad signaling pathway, has been implicated in the pathogenesis of various types of human cancer; however, its role in pancreatic ductal adenocarcinoma (PDAC) has yet to
Melissa A Gray et al.
Nature chemical biology, 16(12), 1376-1384 (2020-08-19)
Currently approved immune checkpoint inhibitor therapies targeting the PD-1 and CTLA-4 receptor pathways are powerful treatment options for certain cancers; however, most patients across cancer types still fail to respond. Consequently, there is interest in discovering and blocking alternative pathways
Tae Kyung Hyun et al.
PloS one, 9(11), e112946-e112946 (2014-11-15)
Despite the completion of the Arabidopsis genome sequence, for only a relatively low percentage of the encoded proteins experimental evidence concerning their function is available. Plant proteins that harbour a single PLAT (Polycystin, Lipoxygenase, Alpha-toxin and Triacylglycerol lipase) domain and
Haitao Shi et al.
Journal of pineal research, 57(2), 185-191 (2014-06-26)
Melatonin (N-acetyl-5-methoxytryptamine) is not only a widely known animal hormone, but also an important regulator in plant development and multiple abiotic stress responses. Recently, it has been revealed that melatonin alleviated cold stress through mediating several cold-related genes, including C-REPEAT-BINDING
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