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Merck
CN

Y0000165

Tribenoside

European Pharmacopoeia (EP) Reference Standard

别名:

Ethyl 3,5,6-tri-O-benzyl-D-glucofuranoside

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关于此项目

经验公式(希尔记法):
C29H34O6
化学文摘社编号:
分子量:
478.58
UNSPSC Code:
41116107
EC Number:
233-687-2
NACRES:
NA.24
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产品名称

Tribenoside, European Pharmacopoeia (EP) Reference Standard

SMILES string

O1[C@@H]([C@@H]([C@H](C1OCC)O)OCc4ccccc4)C(OCc3ccccc3)COCc2ccccc2

InChI key

ULLNJSBQMBKOJH-NUZMXOBKSA-N

InChI

1S/C29H34O6/c1-2-32-29-26(30)28(34-20-24-16-10-5-11-17-24)27(35-29)25(33-19-23-14-8-4-9-15-23)21-31-18-22-12-6-3-7-13-22/h3-17,25-30H,2,18-21H2,1H3/t25?,26-,27-,28-,29?/m1/s1

grade

pharmaceutical primary standard

API family

tribenoside

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

shipped in

wet ice

storage temp.

−20°C

Application

Tribenoside EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

涉药品监管产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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[Test of potential antiarthritic drugs on spontaneous arthritis of mice].
G Wilhelmi et al.
Zeitschrift fur Rheumatologie, 42(4), 203-205 (1983-07-01)
Ia I Khadzhaĭ et al.
Farmakologiia i toksikologiia, 46(2), 72-75 (1983-03-01)
According to the rheo- and photoplethysmography data, ethyl-3,5,6-tri-O-benzyl-D-glucofuranoside (glivenol, tribenol; 25,250 and 4000 mg/kg i.p.) markedly increases the blood content in hind limbs of rabbits, displaying a tendency towards a decrease in systemic arterial pressure and negligibly raises the body
D A Kalbhen et al.
The Journal of rheumatology, 10(2), 267-281 (1983-04-01)
Experiments in adult hens with chemically induced osteoarthrosis or osteoarthritis (OA) of the knee joint have shown that daily treatment with tribenoside (Glyvenol) in single oral doses of 50 mg/kg or 150 mg/kg markedly reduced the intensity and frequency of
Tamás Kubicsek et al.
Reproductive toxicology (Elmsford, N.Y.), 31(4), 464-469 (2010-12-25)
Tribenoside is used for the treatment of haemorrhoids and varicose veins, frequently in pregnant women as well, but published data regarding its possible teratogenic effect are not available. Thus the risk of congenital abnormalities (CAs) was estimated in cases of
L A Chaĭka et al.
Farmakologiia i toksikologiia, 44(1), 74-77 (1981-01-01)
A study was made on the mechanism of action of the antivaricose agent tribenol (ethyl-3,5,6-tri-O-benzyl-D-glucofuranozide; glivenol) on the activity of hydroxyreductase on the Krebs cycle and glycolysis during occlusion of the femoral vein and its inflammation in rats. It was

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