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Merck
CN

Y0000553

多沙唑嗪

European Pharmacopoeia (EP) Reference Standard

别名:

多沙唑嗪 甲磺酸酯, 1-（4-氨基-6,7-二甲氧基-2-喹唑啉基）-4-[4-（1,4-苯并二氧基-2-基）carpiperazin-1-基）]-6,7-二甲氧基喹唑啉 甲磺酸酯, 多沙唑嗪甲磺酸盐

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关于此项目

经验公式（希尔记法）:
C23H25N5O5 · CH3SO3H
化学文摘社编号:
77883-43-3
分子量:
547.58
NACRES:
NA.24
PubChem Substance ID:
329831016
UNSPSC Code:
41116107
MDL number:
MFCD00216023

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产品名称

多沙唑嗪, European Pharmacopoeia (EP) Reference Standard

InChI

1S/C23H25N5O5.CH4O3S/c1-30-18-11-14-15(12-19(18)31-2)25-23(26-21(14)24)28-9-7-27(8-10-28)22(29)20-13-32-16-5-3-4-6-17(16)33-20;1-5(2,3)4/h3-6,11-12,20H,7-10,13H2,1-2H3,(H2,24,25,26);1H3,(H,2,3,4)

SMILES string

CS(O)(=O)=O.COc1cc2nc(nc(N)c2cc1OC)N3CCN(CC3)C(=O)C4COc5ccccc5O4

InChI key

VJECBOKJABCYMF-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

doxazosin

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

Gene Information

human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)

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相关类别

Biochem/physiol Actions

α1-肾上腺素能受体拮抗剂；放松前列腺平滑肌

Application

Doxazosin mesilate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Tanju Keten et al.
Urology, 85(1), 189-194 (2014-12-23)
To compare the efficacy of 4 mg and 8 mg doxazosin XL treatments in patients with benign prostatic hyperplasia-related lower urinary tract symptoms and determine the efficiency of 8 mg in those patients with inadequate response to 4 mg. A

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