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经验公式(希尔记法):
C10H16N6S
化学文摘社编号:
分子量:
252.34
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
产品名称
西咪替丁, European Pharmacopoeia (EP) Reference Standard
InChI
1S/C10H16N6S/c1-8-9(16-7-15-8)5-17-4-3-13-10(12-2)14-6-11/h7H,3-5H2,1-2H3,(H,15,16)(H2,12,13,14)
SMILES string
CN\C(NC#N)=N\CCSCc1nc[nH]c1C
InChI key
AQIXAKUUQRKLND-UHFFFAOYSA-N
grade
pharmaceutical primary standard
API family
cimetidine
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
Gene Information
human ... HRH2(3274)
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Application
Cimetidine for peak identification EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
存储类别
11 - Combustible Solids
wgk
WGK 3
A Kumar
DICP : the annals of pharmacotherapy, 24(3), 289-295 (1990-03-01)
Suppressor T lymphocytes possess histamine2 (H2) receptors and contribute significantly to the function of the immune system. Experimentally, cimetidine, an H2-receptor antagonist, has been shown to enhance a variety of immunologic functions both in vivo and in vitro because of
A F Shinn
Drug safety, 7(4), 245-267 (1992-07-01)
The excellent efficacy and tolerability profiles of H2-antagonists have established these agents as the leading class of antiulcer drugs. Attention has been focused on drug interactions with H2-antagonists as a means of product differentiation and because many patients are receiving
J P Harcourt et al.
International journal of pediatric otorhinolaryngology, 51(2), 109-113 (2000-01-05)
Effective adjuvant treatment for recurrent respiratory papillomatosis (RRP) is at present limited to alpha-interferon, which may have significant side effects including rebound growth of papillomata following its withdrawal, is given by injection and is expensive. High dose cimetidine is known
P San Miguel et al.
Virchows Archiv : an international journal of pathology, 430(3), 261-263 (1997-03-01)
A case of carcinoma in the breast of a male patient with a chronic gastric ulcer is described. The patient had received cimetidine for 17 years. Histological examination of an excisional biopsy showed lobular in situ and infiltrating carcinoma. In
Cimetidine in idiopathic urticaria.
M Choy et al.
DICP : the annals of pharmacotherapy, 25(6), 609-612 (1991-06-01)
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