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Merck
CN

Y0001575

布比卡因杂质F

European Pharmacopoeia (EP) Reference Standard

别名:

2,6-二甲基苯胺, 2,6-二甲苯胺, 2-氨基-1,3-二甲苯, 2-氨基间二甲苯

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线性分子式:
(CH3)2C6H3NH2
化学文摘社编号:
分子量:
121.18
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
636332
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产品名称

布比卡因杂质F, European Pharmacopoeia (EP) Reference Standard

InChI

1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3

SMILES string

Cc1cccc(C)c1N

InChI key

UFFBMTHBGFGIHF-UHFFFAOYSA-N

grade

pharmaceutical primary standard

vapor pressure

<0.01 mmHg ( 20 °C)

API family

bupivacaine

manufacturer/tradename

EDQM

refractive index

n20/D 1.560 (lit.)

bp

214 °C/739 mmHg (lit.)

mp

10-12 °C (lit.)

density

0.984 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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Application

Bupivacaine impurity F EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

195.8 °F - closed cup

flash_point_c

91 °C - closed cup

法规信息

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分析证书(COA)

Lot/Batch Number

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2,6-Dimethylaniline (2,6-xylidine).
IARC monographs on the evaluation of carcinogenic risks to humans, 57, 323-335 (1993-01-01)
Mai Shimizu et al.
Drug metabolism and disposition: the biological fate of chemicals, 42(7), 1103-1109 (2014-04-23)
Esterases catalyze the hydrolysis of therapeutic drugs containing esters or amides in their structures. Human carboxylesterase (CES) and arylacetamide deacetylase (AADAC) are the major enzymes that catalyze the hydrolysis of drugs in the liver. Characterization of the enzyme(s) responsible for

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