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Merck
CN

494496

NMP

biotech. grade, ≥99.7%

别名:

N-甲基-2-吡咯烷酮, N-甲基吡咯烷酮, NMP

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关于此项目

经验公式（希尔记法）:
C5H9NO
化学文摘社编号:
872-50-4
分子量:
99.13
NACRES:
NA.07
PubChem Substance ID:
329757456
UNSPSC Code:
12352005
EC Number:
212-828-1
MDL number:
MFCD00003193
Beilstein/REAXYS Number:
106420
Grade:
biotech. grade
Assay:
≥99.7%
Application(s):
peptide synthesis
Bp:
202 °C (lit.)
81-82 °C/10 mmHg (lit.)
Vapor pressure:
0.29 mmHg ( 20 °C)
0.99 mmHg ( 40 °C)

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产品名称

1-甲基-2-吡咯烷酮, biotech. grade, ≥99.7%

InChI key

SECXISVLQFMRJM-UHFFFAOYSA-N

InChI

1S/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3

SMILES string

CN1CCCC1=O

grade

biotech. grade

vapor density

3.4 (vs air)

vapor pressure

0.29 mmHg ( 20 °C)
0.99 mmHg ( 40 °C)

assay

≥99.7%

form

liquid

autoignition temp.

518 °F

expl. lim.

9.5 %

impurities

≤0.005% water
≤0.01% free amines (CH3NH2)

color

APHA: ≤20

refractive index

n20/D 1.47 (lit.)

pH

7.7-10.0 (20 °C, 100 g/L)

bp

202 °C (lit.)
81-82 °C/10 mmHg (lit.)

mp

−24 °C (lit.)

solubility

acetone: miscible(lit.)
alcohol: miscible(lit.)
chloroform: miscible(lit.)
ethyl acetate: miscible(lit.)
water: miscible(lit.)

density

1.028 g/mL at 25 °C (lit.)

λ

H2O reference

UV absorption

λ: 285 nm Amax: 1.00
λ: 300 nm Amax: 0.50
λ: 325 nm Amax: 0.10
λ: 350-400 nm Amax: 0.01

application(s)

peptide synthesis

Quality Level

100

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相关类别

General description

N -甲基-2-吡咯烷酮（ N -甲基吡咯烷酮，NMP）是一种极性环状有机溶剂。一项关于 NMP 对 酿酒酵母影响的研究 发现其可诱导非整倍体。NMP 的特性属性粘度低、溶解性能好、破乳属性增强。它是选择性处理润滑油原料的一种较好的替代苯酚的方法。基于电子吸收和光致发光光谱数据，研究了富勒烯-C 60 在 NMP 溶液中的行为。硼氢化钠 (NaBH 4 ) 的 NMP 溶液对烷基溴的脱溴反应活性增加。用气相色谱法分析了 NMP-乙二醇混合溶剂对芳烃抽提的增强选择性。
Our biotech solvents offer exceptional quality for reliable RNA extraction, ensuring optimal laboratory performance. With low water content and minimal residue, give clean UV spectra to minimize contamination.
  • High-Quality Biotech Solvents: Designed for optimal laboratory performance with low water content and minimal residues.
  • Ideal for RNA Extraction: Essential for genetic testing and research applications like PCR.
  • Ensures Integrity of Genetic Material: Promotes reliable and reproducible results.
  • Industry Compliant: Suitable for both academic and commercial laboratories, enhancing research efficiency.

Packaging

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pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 1

flash_point_f

195.8 °F - Pensky-Martens closed cup

flash_point_c

91 °C - Pensky-Martens closed cup

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
SHBT3956
SHBS9223
SHBS9015
SHBS7784
SHBS4184

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NaBH4 in N-methylpyrrolidone: a safe alternative for hydride displacement reaction.
Torisawa Y, et al.
Bioorganic & Medicinal Chemistry Letters, 11(20), 2787-2789 (2001)
Evaluation of extraction properties of N-methylpyrrolidone and ethylene glycol mixtures by gas chromatography.
Wardencki W and Tameesh AHH.
Journal of Chemical Technology and Biotechnology, 31(1), 86-92 (1981)
Sanjairaj Vijayavenkataraman et al.
Artificial organs, 43(5), 515-523 (2018-09-20)
The incidence of peripheral nerve injuries is on the rise and the current gold standard for treatment of such injuries is nerve autografting. Given the severe limitations of nerve autografts which include donor site morbidity and limited supply, neural guide
N-methylpyrrolidone instead of phenol in treatment of lube feedstock.
Ivanov AV, et al.
Chemistry and Technology of Fuels and Oils, 36(5), 352-354 (2000)
Aggregation of fullerene C60 in N-methylpyrrolidone.
Yevlampieva NP, et al.
Colloids and Surfaces. A, Physicochemical and Engineering Aspects, 209(2), 167-171 (2002)
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