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Merck
CN

01423

N-乙酰基-D-青霉胺

≥99.0% (T)

别名:

NAP, NAPA, N-乙酰基-3-巯基-D-缬氨酸

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关于此项目

经验公式(希尔记法):
C7H13NO3S
化学文摘社编号:
分子量:
191.25
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352116
EC Number:
239-585-4
MDL number:
Beilstein/REAXYS Number:
1724742
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产品名称

N-乙酰基-D-青霉胺, ≥99.0% (T)

SMILES string

CC(=O)N[C@@H](C(O)=O)C(C)(C)S
CC(=O)N[C@@H](C(O)=O)C(C)(C)S

InChI key

MNNBCKASUFBXCO-YFKPBYRVSA-N

InChI

1S/C7H13NO3S/c1-4(9)8-5(6(10)11)7(2,3)12/h5,12H,1-3H3,(H,8,9)(H,10,11)/t5-/m0/s1

grade

derivatization grade ((HPLC))

assay

≥99.0% (T)

form

powder or crystals

optical activity

[α]20/D +10±2°, c = 1% in ethanol

technique(s)

HPLC: suitable (derivatization)

color

white

mp

185-190 °C (dec.)

application(s)

peptide synthesis

Quality Level

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Application

用于氨基酸或氨基醇柱前衍生化的手性试剂;所形成的非对映异构体可在常规反相色谱柱上通过HPLC高效分离

Biochem/physiol Actions

N-乙酰-D-青霉胺(NAP或NAPA)是一种硫醇化合物,在涉及一氧化氮供体分子(如S-亚硝基-N-乙酰-dl-青霉胺(SNAP)和硝普钠(SNP))的研究中,常被用作对照分子。N-乙酰-D-青霉胺(NAPA)也被用作重金属螯合剂。

Other Notes

探索最适于 HPLCLC-MS 分析的LiChropur试剂

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Xiao Lin et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(26), 6717-6721 (2017-06-15)
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Activity-dependent neuroprotective protein (ADNP), vital for brain formation and cognitive function, is mutated in autism and linked to neurodegenerative/psychiatric diseases. An eight-amino-acid peptide snippet of ADNP, NAP (NAPVSIPQ), identified as a smallest active fragment, includes the SxIP microtubule (MT) end-binding
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PLoS medicine, 8(3), e1000427-e1000427 (2011-03-23)
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