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Merck
CN

10419

8-苯胺基-1-萘磺酸 半镁盐 水合物

suitable for fluorescence, ≥95.0% (T)

别名:

8-苯胺-1-萘磺酸镁 水合物, ANSA 镁盐, N-苯基-1-萘胺-8-磺酸 镁盐, 苯基-1-萘胺-8-磺酸 镁盐

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关于此项目

经验公式（希尔记法）:
C16H12Mg0.5NO3S · xH2O
化学文摘社编号:
18108-68-4
分子量:
310.49 (anhydrous basis)
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
329749053
EC Number:
242-004-7
Beilstein/REAXYS Number:
4834623
MDL number:
MFCD16661224

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产品名称

8-苯胺基-1-萘磺酸 半镁盐 水合物, suitable for fluorescence, ≥95.0% (T)

InChI key

FBANPIUXAXTAFX-UHFFFAOYSA-L

InChI

1S/2C16H13NO3S.Mg.H2O/c2*18-21(19,20)15-11-5-7-12-6-4-10-14(16(12)15)17-13-8-2-1-3-9-13;;/h2*1-11,17H,(H,18,19,20);;1H2/q;;+2;/p-2

SMILES string

O.[Mg++].[O-]S(=O)(=O)c1cccc2cccc(Nc3ccccc3)c12.[O-]S(=O)(=O)c4cccc5cccc(Nc6ccccc6)c45

assay

≥95.0% (T)

form

powder

technique(s)

titration: suitable

solubility

hot water: 50 mg/mL, green

λmax

465-475 nm

fluorescence

λex 388 nm; λem 470 nm in 0.1 M Tris, 0.2 M KCl, pH 9.0, BSA

suitability

suitable for fluorescence

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

Quality Level

200

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相关类别

Features and Benefits

用于估算表面活性剂CMC的荧光探针。

General description

ANSA (8-Anilino-1-naphthalensulfonic acid) 是一种疏水性极性敏感的荧光染料，可作为位点探针用于检测细胞和胶束膜以及蛋白质等分子的构象变化。ANSA 也用作荧光探针，用于估算表面活性剂的临界胶束浓度 (CMC)。

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCN2524
BCCM6782
BCCL1990
BCCK8670
BCCK2567

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M Bertsch et al.
Analytical biochemistry, 313(2), 187-195 (2003-02-28)
Hydrophobic sites on the surface of protein molecules are thought to have important functional roles. The identification of such sites can provide information about the function and mode of interaction with other cellular components. While the fluorescence enhancement of polarity-sensitive
C D Peters et al.
Biochemistry and cell biology = Biochimie et biologie cellulaire, 75(1), 55-61 (1997-01-01)
Protein aggregation is believed to be due to conformers that expose hydrophobic clusters that promote protein association. Such conformers can be detected using a fluorescent probe like 8-anilino 1-naphthalenesulfonic acid (ANSA). Here we show that urease exposed to 1.0 M
Rapid fluorescent "staining" of nondenatured protein bands in agar and polyacrylamide gels.
S T Nerenberg et al.
Analytical biochemistry, 43(2), 564-574 (1971-10-01)
J L Jensen et al.
Cellular and molecular biology (Noisy-le-Grand, France), 46(3), 685-696 (2000-06-29)
We have studied the metal-catalyzed oxidation (MCO) of brain-derived neurotrophic factor (BDNF) with regard to target sites and potential conformational changes of the protein. The exposure of BDNF to three different levels of ascorbate/Cu(II)/O2 [20 microM Cu(II), 2 mM ascorbate
Anilinonaphthalene sulfonate as a probe of membrane composition and function.
J Slavík
Biochimica et biophysica acta, 694(1), 1-25 (1982-08-11)
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