产品名称
Atto 488 马来酰亚胺, BioReagent, suitable for fluorescence, ≥90% (HPLC)
product line
BioReagent
assay
≥90% (HPLC)
≥90% (degree of coupling )
manufacturer/tradename
ATTO-TEC GmbH
λ
in methanol: water (1:1) (with 0.1% perchloric acid)
UV absorption
λ: 501-506 nm Amax
suitability
suitable for fluorescence
storage temp.
−20°C
Quality Level
Application
Atto 488马来酰亚胺用于标记胺，其要求的pH值高于马来酰亚胺和硫醇反应的pH值。它非常适合硫醇基团的荧光标记。
General description
Atto 488马来酰亚胺是一种亲水的荧光标记，具有高分子吸收（90.000）和量子产率（0.80）。在最大501纳米下可激发其荧光活性，523纳米下达到最大发射率。 Atto 488马来酰亚胺针对氩激光器的激发进行了优化，并具有高光稳定性。马来酰亚胺水解形成同分异构的无活性马来酸混合物的反应在硫醇修饰后可以大体完成，在pH高于8的条件下更是如此。偶联至底物后，该标记物携带-1的净电荷。
Legal Information
本产品仅供研究使用。如果打算商业化，请联系知识产权持有者（德国ATTO-TEC GmbH公司）申请许可。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Analysis of fluorescent nanostructures in biological systems by means of spectral position determination microscopy (SPDM).
Muller, P., et al. et al.
Current Microscopy Contributions to Advances in Science and Technology, 1, 3-12 (2012)
E Pourkarimi et al.
Cell death and differentiation, 19(3), 406-415 (2011-09-03)
In C. elegans, the BH3-only domain protein EGL-1, the Apaf-1 homolog CED-4 and the CED-3 caspase are required for apoptosis induction, whereas the Bcl-2 homolog CED-9 prevents apoptosis. Mammalian B-cell lymphoma 2 (Bcl-2) inhibits apoptosis by preventing the release of
Sonal et al.
Journal of cell science, 132(4) (2018-12-13)
Dynamic reorganization of the actomyosin cytoskeleton allows fast modulation of the cell surface, which is vital for many cellular functions. Myosin-II motors generate the forces required for this remodeling by imparting contractility to actin networks. However, myosin-II activity might also
Markus Hirsch et al.
Biological chemistry, 393(1-2), 23-35 (2012-05-26)
Investigations into the fate of small interfering RNA (siRNA) after transfection may unravel new ways to improve RNA interference (RNAi) efficiency. Because intracellular degradation of RNA may prevent reliable observation of fluorescence-labeled siRNA, new tools for fluorescence microscopy are warranted
Jeanne C Stachowiak et al.
Nature cell biology, 14(9), 944-949 (2012-08-21)
Curved membranes are an essential feature of dynamic cellular structures, including endocytic pits, filopodia protrusions and most organelles. It has been proposed that specialized proteins induce curvature by binding to membranes through two primary mechanisms: membrane scaffolding by curved proteins
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持