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Merck
CN
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安全信息

31170

Sigma-Aldrich

2-脱氧-D-核糖

≥99.0% (TLC)

别名:

2-脱氧-D-赤戊糖, D-2-脱氧核糖, 胸腺糖

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About This Item

经验公式(希尔记法):
C5H10O4
CAS Number:
分子量:
134.13
Beilstein:
1721978
EC 号:
MDL编号:
UNSPSC代码:
12352201
PubChem化学物质编号:
NACRES:
NA.25

价格与库存信息目前不能提供

质量水平

方案

≥99.0% (TLC)

表单

solid

旋光性

[α]20/D −56±2°, 24 hr, c = 1% in H2O

杂质

<0.5% Sulphated ash

灼烧残渣

≤0.5% (as SO4)

缺失

≤1% loss on drying, 20 °C (HV)

颜色

white

mp

89-90 °C (lit.)

溶解性

water: 50 mg/mL, clear, colorless to faintly yellow

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应用

2-Deoxy-D-ribose is used to study processes of oxidative stress and glycation in vivo and in vitro. 2-Deoxy-D-ribose, an endothelial-cell chemoattractant and angiogenesis-inducing factor, is used to study processes of tumor angiogenesis and progression mediated at the level of thymidine phosphorylase activity.

其他说明

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

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  • 历史批次信息供参考:

    分析证书(COA)

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    Xican Li
    Food chemistry, 141(3), 2083-2088 (2013-07-23)
    The deoxyribose degradation assay is widely used to evaluate the hydroxyl (OH) radical-scavenging ability of food or medicines. We compared the hydroxyl radical-scavenging activity of 25 antioxidant samples prepared in ethanol solution with samples prepared after removing the ethanol (residue).
    Marina Rossi et al.
    Physical review letters, 110(10), 107801-107801 (2013-03-26)
    Concentrated solutions of ultrashort duplex-forming DNA oligomers may develop various forms of liquid crystal ordering among which is the chiral nematic phase, characterized by a macroscopic helical precession of molecular orientation. The specifics of how chirality propagates from the molecular
    Jean Cadet et al.
    Free radical research, 46(4), 367-381 (2012-01-24)
    A broad scientific community is involved in investigations aimed at delineating the mechanisms of formation and cellular processing of oxidatively generated damage to nucleic acids. Perhaps as a consequence of this breadth of research expertise, there are nomenclature problems for
    Katarzyna Lamparska et al.
    Nucleic acids research, 40(19), 9788-9801 (2012-08-02)
    5-Aza-2'-deoxycytidine (5azaC-dR) has been employed as an inhibitor of DNA methylation, a chemotherapeutic agent, a clastogen, a mutagen, an inducer of fragile sites and a carcinogen. However, its effects are difficult to quantify because it rapidly breaks down in aqueous
    Guillaume Mata et al.
    The Journal of organic chemistry, 77(20), 9006-9017 (2012-09-15)
    An efficient method for the N-2-deoxyribosylation of modified nucleobases by 2-deoxythioriboside donors is reported. In the presence of an in situ silylated nucleobase, thioglycosides can be activated with NIS/HOTf to give nucleosides in high yields and with good β-selectivity. By

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