39286
羟基司替丁双（甲磺酸酯）
suitable for fluorescence, ≥96.0% (HPLC)
别名:
2-羟基二苯乙烯-4,4′-二羧氨基脒双（甲磺酸）, 氟金, 2-羟基二苯乙烯-4,4′-二羧氨基脒双, 氟金™
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关于此项目
经验公式（希尔记法）:
C18H24N4O7S2
化学文摘社编号:
分子量:
472.54
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
41116100
MDL number:
产品名称
羟基司替丁双（甲磺酸酯）, suitable for fluorescence, ≥96.0% (HPLC)
InChI
1S/C16H16N4O.2CH4O3S/c17-15(18)12-5-2-10(3-6-12)1-4-11-7-8-13(16(19)20)9-14(11)21;2*1-5(2,3)4/h1-9,21H,(H3,17,18)(H3,19,20);2*1H3,(H,2,3,4)/b4-1+;;
SMILES string
CS(O)(=O)=O.CS(O)(=O)=O.NC(=N)c1ccc(cc1)\C=C\c2ccc(cc2O)C(N)=N
InChI key
YGNSQKCULHSJDC-HFPMQDOPSA-N
assay
≥96.0% (HPLC)
form
powder
fluorescence
λex 318 nm; λem 560 nm in TBE Buffer
suitability
suitable for fluorescence
storage temp.
2-8°C
Quality Level
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Application
羟基苯胺双（甲磺酸）或荧光金（FG）可用于标记神经元，并研究听力损失的早期影响。它可用于通过标记细胞来研究CNS内广泛轴突投射的形态学特征。
羟芪巴脒双（甲磺酸）是一种荧光逆行示踪剂（轴突转运），在显微解剖学研究中用于神经定位。
General description
羟基苯胺双（甲磺酸），又称荧光金，是一种逆行荧光示踪剂。在化学上，羟基苯胺是一种弱碱，可以其不带电的形式穿过细胞膜。
羟基苯胺双（甲磺酸）的部分性质包括：
羟基苯胺双（甲磺酸）的部分性质包括：
- 强烈的荧光反应。
- 广泛树突填充。
- 较高的抗褪色性。
- 未受损纤维无法吸收。
- 标记细胞不扩散。
- 与其他神经组织化学技术高度兼容。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
M W Wessendorf
Brain research, 553(1), 135-148 (1991-07-05)
Determining the mechanism by which fluorescent retrograde neuronal tracers are taken up requires knowledge of their composition. It has been claimed that Fluoro-Gold, a retrogradely transported fluorescent neuronal tracer, is 2-hydroxy-4,4'-diamidinostilbene (hydroxystilbamidine), an amidine antibiotic. However, this appears questionable, since
N Kuwabara
Biotechnic & histochemistry : official publication of the Biological Stain Commission, 87(6), 413-422 (2012-06-21)
A method is described for studying the morphological features of extensive axonal projections within the central nervous system of the gerbil, Meriones anguiculatus. Potentially long descending axonal projections between the auditory thalamus and lower brainstem were used as a model.
Lijie Chen et al.
Experimental and therapeutic medicine, 4(5), 844-848 (2012-12-12)
Understanding the microanatomy of the facial nerve is vital to functional restoration of facial nerve injury. This study aimed to locate the spatial orientation of five branches in the extratemporal trunk of the rat facial nerve (ETFN). Fifteen adult Sprague-Dawley
Miyako Hatano et al.
Hearing research, 287(1-2), 57-66 (2012-06-26)
The purpose of this study was to investigate the effects of early hearing loss on the anatomy of the central auditory system, specifically, the ascending projections to the inferior colliculus (IC). We compared normal animals with animals deafened during early
L C Schmued et al.
Brain research, 377(1), 147-154 (1986-07-02)
A new fluorescent dye, Fluoro-Gold, has been demonstrated to undergo retrograde axonal transport. Its properties include intense fluorescence, extensive filling of dendrites, high resistance to fading, no uptake by intact undamaged fibers of passage, no diffusion from labeled cells, consistent
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