46943
Fluorescein dilaurate
suitable for fluorescence, ≥97.0% (HPCE)
质量水平
方案
≥97.0% (HPCE)
表单
powder
溶解性
ethanol: soluble
荧光
λex 490 nm; λem 514 nm in 0.1 M Tris pH 8.0 (esterase)
适用性
suitable for fluorescence
SMILES字符串
CCCCCCCCCCCC(=O)Oc1ccc2c(Oc3cc(OC(=O)CCCCCCCCCCC)ccc3C24OC(=O)c5ccccc45)c1
InChI
1S/C44H56O7/c1-3-5-7-9-11-13-15-17-19-25-41(45)48-33-27-29-37-39(31-33)50-40-32-34(49-42(46)26-20-18-16-14-12-10-8-6-4-2)28-30-38(40)44(37)36-24-22-21-23-35(36)43(47)51-44/h21-24,27-32H,3-20,25-26H2,1-2H3
InChI key
MYTRGBGGRICZGN-UHFFFAOYSA-N
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应用
Fluorescein dilaurate is suitable as fluorogenic substrate for esterases/lipases and used in the pancreolauryl test for chronic pancreatitis.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
F Seibold et al.
Journal of clinical gastroenterology, 22(3), 202-206 (1996-04-01)
Pancreatic autoantibodies (PABs) are found in 31% of patients with Crohn's disease (CD), but they do not correlate with the activity of intestinal disease or the incidence of acute pancreatitis. Exocrine pancreatic insufficiency has been observed in patients with CD.
J E Domínguez-Muñoz et al.
Clinical chemistry, 44(4), 869-875 (1998-05-15)
The serum pancreolauryl test has limited sensitivity for detecting mild pancreatic insufficiency. The aim of this study was to optimize the serum pancreolauryl test so as to increase the probability of positive results in patients with chronic pancreatitis. The study
I A Murray et al.
Postgraduate medical journal, 79(934), 471-473 (2003-09-05)
To audit the specificity and value of the pancreolauryl test (PLT) for the diagnosis of pancreatic insufficiency. A retrospective case note review of 47 patients who had a PLT during three consecutive years. A 650 bedded district general hospital. Patient
M Fuchs et al.
Zentralblatt fur Chirurgie, 120(6), 472-477 (1995-01-01)
In a follow up study 19 patients after Billroth-I, 22 patients after Billroth-II-resection and 38 patients after total gastrectomy (23 with Roux-Y-reconstruction and 15 with Longmire-Gütgemann) underwent a stool fat determination and an indirect pancreatic function test with fluorescein dilaurate
L M Burrell et al.
Scandinavian journal of clinical and laboratory investigation, 51(8), 675-680 (1991-12-01)
We have employed an oral test of pancreatic digestive function using fluorescein dilaurate (a substrate for pancreatic cholesterol ester hydrolase), administered together with pancreatic enzyme supplements, in order to test the hypothesis that urinary excretion of fluorescein provides a simple
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