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Merck
CN

46943

Fluorescein dilaurate

suitable for fluorescence, ≥97.0% (HPCE)

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关于此项目

经验公式(希尔记法):
C44H56O7
化学文摘社编号:
分子量:
696.91
Beilstein:
6034843
EC 号:
MDL编号:
UNSPSC代码:
12352106
PubChem化学物质编号:
NACRES:
NA.32
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质量水平

方案

≥97.0% (HPCE)

表单

powder

溶解性

ethanol: soluble

荧光

λex 490 nm; λem 514 nm in 0.1 M Tris pH 8.0 (esterase)

适用性

suitable for fluorescence

SMILES字符串

CCCCCCCCCCCC(=O)Oc1ccc2c(Oc3cc(OC(=O)CCCCCCCCCCC)ccc3C24OC(=O)c5ccccc45)c1

InChI

1S/C44H56O7/c1-3-5-7-9-11-13-15-17-19-25-41(45)48-33-27-29-37-39(31-33)50-40-32-34(49-42(46)26-20-18-16-14-12-10-8-6-4-2)28-30-38(40)44(37)36-24-22-21-23-35(36)43(47)51-44/h21-24,27-32H,3-20,25-26H2,1-2H3

InChI key

MYTRGBGGRICZGN-UHFFFAOYSA-N

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相关类别

应用

Fluorescein dilaurate is suitable as fluorogenic substrate for esterases/lipases and used in the pancreolauryl test for chronic pancreatitis.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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F Seibold et al.
Journal of clinical gastroenterology, 22(3), 202-206 (1996-04-01)
Pancreatic autoantibodies (PABs) are found in 31% of patients with Crohn's disease (CD), but they do not correlate with the activity of intestinal disease or the incidence of acute pancreatitis. Exocrine pancreatic insufficiency has been observed in patients with CD.
Z Wójcik et al.
Polski tygodnik lekarski (Warsaw, Poland : 1960), 50(1-35), 791-793 (1995-01-01)
Fifteen patients with chronic pancreatitis were qualified for surgical treatment on the basis of the results of endoscopic retrograde cholangiopancreatography, pancreolauryl test and glucose tolerance test. Significant changes according to Cambridge scale correlated with exocrine-endocrine pancreatic failure. In patients with
D A Elphick et al.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 5(2-3), 196-200 (2005-04-26)
The urine pancreolauryl ratio (uPLR) and, more recently, the faecal pancreatic elastase-1, are widely used for the noninvasive diagnosis of exocrine pancreatic insufficiency. Both tests have previously been validated against 'gold standard' tests of pancreatic function, but their use in
A L Trewick
Annals of clinical biochemistry, 35 ( Pt 2), 274-278 (1998-04-21)
The influence of the glucose concentration in urines being assayed as part of a pancreolauryl test was investigated. Paired patient urines (n = 5) were assayed at 60 degrees and 70 degrees C, before and after spiking to 5% glucose.
E Małecka-Panas et al.
Polskie Archiwum Medycyny Wewnetrznej, 94(4), 315-323 (1995-10-01)
The aim of the presented study was a comparative evaluation of the three indirect pancreatic function tests: pancreolauryl-test (PLT), NBT-PABA test and faecal chymotrypsin (CH) efficacy in detecting pancreatic exocrine function impairment in advanced chronic pancreatitis (acp). 30 patients with

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