46985
荧光素-5-氨基硫脲
suitable for fluorescence, ~80% (HPCE)
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关于此项目
经验公式（希尔记法）:
C21H15N3O5S
化学文摘社编号:
分子量:
421.43
MDL编号:
UNSPSC代码:
12352125
PubChem化学物质编号:
NACRES:
NA.32
方案
~80% (HPCE)
质量水平
表单
solid
溶解性
DMF: soluble
H2O: soluble
荧光
λex 492 nm; λem 516 nm in 0.1 M Tris pH 9.0
适用性
suitable for fluorescence
储存温度
−20°C
SMILES字符串
NNC(=S)Nc1ccc(c(c1)C(O)=O)C2=C3C=CC(=O)C=C3Oc4cc(O)ccc24
InChI
1S/C21H15N3O5S/c22-24-21(30)23-10-1-4-13(16(7-10)20(27)28)19-14-5-2-11(25)8-17(14)29-18-9-12(26)3-6-15(18)19/h1-9,25H,22H2,(H,27,28)(H2,23,24,30)
InChI key
MEUCHQDLZYLNQY-UHFFFAOYSA-N
一般描述
荧光素-5-氨基硫脲，也称为 FTC，是一种荧光探针。FTSC 荧光光谱类似于 FITC，这是蛋白质组学的优选荧光标签。 通过还原胺化获得的 FTSC 标记囊泡的荧光光谱特性与荧光仪器的氩激光完全兼容。
应用
荧光素-5- 氨基硫脲可用作荧光标记试剂，以标记：
- 细胞表面官能团（血型糖蛋白），以研究红细胞膜脱氧的影响。
- 适用于活细胞多糖成像的糖类。
- 适用于细胞特异性给药应用中的硫酸软骨素纳米凝胶。
特点和优势
荧光素-5-氨基硫脲具有以下优点-
- 它显示出强烈的荧光特性。
- 显示了氨基硫脲基团对醛基的固有反应性。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
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Zhang Y, et al.
Carbohydrate Research, 346(14), 2156-2164 (2011)
Injectable hydrogel-incorporated cancer cell-specific cisplatin releasing nanogels for targeted drug delivery
Gil MS, et al.
Journal of Material Chemistry B: Materials for Biology and Medicine, 5(34), 7140-7152 (2017)
Deoxygenation affects fluorescence photobleaching recovery measurements of red cell membrane protein lateral mobility
Corbett JD, et al.
Biophysical Journal, 66(1), 25-30 (1994)
Hua Tian et al.
Journal of cellular and molecular medicine, 21(1), 107-120 (2016-08-12)
Oxidative stress and inflammation play important roles in the pathogenesis of cardiovascular disease (CVD). Oxidative stress-induced desialylation is considered to be a primary step in atherogenic modification, and therefore, the attenuation of oxidative stress and/or inflammatory reactions may ameliorate CVD.
J D Corbett et al.
Biophysical journal, 66(1), 25-30 (1994-01-01)
We have used the fluorescence photobleaching recovery technique to study the dependence on oxygen tension of the lateral mobility of fluorescently labeled band 3, the phospholipid analogue fluorescein phosphatidylethanolamine, and glycophorins in normal red blood cell membranes. Band 3 protein
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