46985
荧光素-5-氨基硫脲
suitable for fluorescence, ~80% (HPCE)
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关于此项目
经验公式（希尔记法）:
C21H15N3O5S
化学文摘社编号:
分子量:
421.43
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352125
MDL number:
产品名称
荧光素-5-氨基硫脲, suitable for fluorescence, ~80% (HPCE)
InChI
1S/C21H15N3O5S/c22-24-21(30)23-10-1-4-13(16(7-10)20(27)28)19-14-5-2-11(25)8-17(14)29-18-9-12(26)3-6-15(18)19/h1-9,25H,22H2,(H,27,28)(H2,23,24,30)
SMILES string
NNC(=S)Nc1ccc(c(c1)C(O)=O)C2=C3C=CC(=O)C=C3Oc4cc(O)ccc24
InChI key
MEUCHQDLZYLNQY-UHFFFAOYSA-N
assay
~80% (HPCE)
form
solid
solubility
DMF: soluble
H2O: soluble
fluorescence
λex 492 nm; λem 516 nm in 0.1 M Tris pH 9.0
suitability
suitable for fluorescence
storage temp.
−20°C
Quality Level
Application
荧光素-5- 氨基硫脲可用作荧光标记试剂，以标记：
- 细胞表面官能团（血型糖蛋白），以研究红细胞膜脱氧的影响。
- 适用于活细胞多糖成像的糖类。
- 适用于细胞特异性给药应用中的硫酸软骨素纳米凝胶。
Features and Benefits
荧光素-5-氨基硫脲具有以下优点-
- 它显示出强烈的荧光特性。
- 显示了氨基硫脲基团对醛基的固有反应性。
General description
荧光素-5-氨基硫脲，也称为 FTC，是一种荧光探针。FTSC 荧光光谱类似于 FITC，这是蛋白质组学的优选荧光标签。 通过还原胺化获得的 FTSC 标记囊泡的荧光光谱特性与荧光仪器的氩激光完全兼容。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Ying Zhang et al.
Carbohydrate research, 346(14), 2156-2164 (2011-08-10)
A simple and efficient procedure for the fluorescent labeling of saccharides is a prerequisite step for imaging the transport of polysaccharides in living cells. We report a one-pot strategy for the fluorescent labeling of saccharides with fluorescein-5-thiosemicarbazide (FTSC), which introduces
M Havé et al.
Plant biology (Stuttgart, Germany), 17(5), 973-979 (2015-02-17)
Leaf senescence is characterised by a massive degradation of proteins in order to recycle nitrogen to other parts of the plant, such as younger leaves or developing grain/seed. Protein degradation during leaf senescence is a highly regulated process and it
Shinichi Nishimura et al.
PloS one, 8(12), e83716-e83716 (2014-01-05)
Cholesterol plays important roles in biological membranes. The cellular location where cholesterol molecules work is prerequisite information for understanding their dynamic action. Bioimaging probes for cholesterol molecules would be the most powerful means for unraveling the complex nature of lipid
One-pot fluorescent labeling of saccharides with fluorescein-5-thiosemicarbazide for imaging polysaccharides transported in living cells
Zhang Y, et al.
Carbohydrate Research, 346(14), 2156-2164 (2011)
Deoxygenation affects fluorescence photobleaching recovery measurements of red cell membrane protein lateral mobility
Corbett JD, et al.
Biophysical Journal, 66(1), 25-30 (1994)
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