49225
α-D-Glucose 1,6-bisphosphate potassium salt hydrate
≥99.0% (TLC)
别名:
α-D-Glucose 1,6-diphosphate potassium salt hydrate
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关于此项目
经验公式（希尔记法）:
C6H10K4O12P2 · xH2O
化学文摘社编号:
分子量:
492.48 (anhydrous basis)
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352201
MDL number:
产品名称
α-D-Glucose 1,6-bisphosphate potassium salt hydrate, ≥99.0% (TLC)
InChI key
OVRXVCAVDXBPQT-QMKHLHGBSA-J
SMILES string
[K+].[K+].[K+].[K+].O[C@H]1[C@H](O)[C@@H](COP([O-])([O-])=O)O[C@H](OP([O-])([O-])=O)[C@@H]1O
InChI
1S/C6H14O12P2.4K/c7-3-2(1-16-19(10,11)12)17-6(5(9)4(3)8)18-20(13,14)15;;;;/h2-9H,1H2,(H2,10,11,12)(H2,13,14,15);;;;/q;4*+1/p-4/t2-,3-,4+,5-,6-;;;;/m1..../s1
assay
≥99.0% (TLC)
form
solid
impurities
≤15% water
color
white
solubility
H2O: 50 mg/mL, clear, colorless
storage temp.
−20°C
Quality Level
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Application
α-D-Glucose 1,6-bisphosphate is used in the identification, differentiation and characterization of α-phosphoglucomutase(s), β-phosphoglucomutase(s) and α- and β-hexoglucomutase(s).
Biochem/physiol Actions
Metabolite formed via the activity of Glucose-1,6-biphosphate synthase. Glucose-1,6-biphosphate (G-1,6-BP) acts as an inhibitor of hexokinase function and an activator of phosphofructokinase-1 and pyruvate kinase. G-1,6-BP also acts as a coenzyme for phosphoglucomutate and a cofactor for phosphopentomutase.
Other Notes
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
涉药品监管产品
此项目有
Jessica P Lao et al.
G3 (Bethesda, Md.), 9(2), 413-423 (2018-12-12)
Phosphomannomutase 2 Deficiency (PMM2-CDG) is the most common monogenic congenital disorder of glycosylation (CDG) affecting at least 800 patients globally. PMM2 orthologs are present in model organisms, including the budding yeast Saccharomyces cerevisiae gene SEC53 Here we describe conserved genotype-phenotype
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