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Merck
CN

49667

Sigma-Aldrich

4-(马来酰亚胺基)苯基异氰酸酯

purum, ≥97.0% (CHN)

别名:

N-(4-异氰酸苯基)马来酰亚胺, PMPI

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关于此项目

经验公式(希尔记法):
C11H6N2O3
化学文摘社编号:
分子量:
214.18
MDL编号:
UNSPSC代码:
12352106
PubChem化学物质编号:
NACRES:
NA.25
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等级

purum

质量水平

方案

≥97.0% (CHN)

表单

solid

反应适用性

reagent type: linker

mp

120-125 °C

官能团

maleimide

储存温度

2-8°C

SMILES字符串

O=C(C=C1)N(C(C=C2)=CC=C2N=C=O)C1=O

InChI

1S/C11H6N2O3/c14-7-12-8-1-3-9(4-2-8)13-10(15)5-6-11(13)16/h1-6H

InChI key

OJQSISYVGFJJBY-UHFFFAOYSA-N

包装

无底玻璃瓶。内含物装在插入的融合锥内。

其他说明

一种新的异双官能团羟基巯基偶联物

象形图

Health hazardExclamation mark

警示用语:

Danger

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Stéphane G Lévesque et al.
Bioconjugate chemistry, 18(3), 874-885 (2007-04-04)
Hydrogels derived from synthetic polymers have been previously engineered to degrade under the activity of matrix metalloproteinases (MMPs). It is believed that these systems can act as extracellular-matrix (ECM) equivalents mimicking the degradation and remodeling of the ECM through the
Luciano Dibona-Villanueva et al.
Journal of agricultural and food chemistry, 69(3), 945-954 (2021-01-14)
A novel chemical conjugate between chitosan (CH) and riboflavin (RF) has been synthesized and characterized via Fourier transform infrared, NMR, and other spectroscopic methods. Photophysical and photochemical properties such as absorption spectra, fluorescence emission, fluorescence anisotropy, and singlet oxygen generation
T-W Cha et al.
Analytical biochemistry, 311(1), 27-32 (2002-11-21)
High-density poly(ethylene glycol) (PEG) molecules are grafted onto Si surfaces in a brush-like configuration. We demonstrate that this surface is an excellent substrate for oligonucleotide immobilization. p-Maleimidophenyl isocyanate is used as a heterobifunctional cross-linker to tether thiol-modified oligonucleotides to terminal
M E Annunziato et al.
Bioconjugate chemistry, 4(3), 212-218 (1993-05-01)
p-Maleimidophenyl isocyanate (PMPI, 1) is a heterobifunctional cross-linking agent useful for thiol to hydroxyl coupling. Several maleimide-activated compounds were prepared and characterized and then shown to be reactive with thiol-containing proteins. Examples include activation of vitamin B12, digoxigenin, digitoxigenin, estradiol
B N Manjula et al.
The Journal of biological chemistry, 275(8), 5527-5534 (2000-02-22)
Bis(maleidophenyl)-PEG2000 (Bis-Mal-PEG2000), a new bifunctional protein cross-linker targeted to sulfhydryl groups, introduces intra-tetrameric cross-links into oxy-HbA in nearly quantitative yields. Structural as well as crystallographic analyses of the cross-linked species, Bis-Mal-PEG2000 HbA, identified Cys-93(beta) as the site of intramolecular cross-linking.

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