登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式(希尔记法):
C5H9NO3
化学文摘社编号:
分子量:
131.13
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
200-091-9
MDL number:
Beilstein/REAXYS Number:
81441
产品名称
反式 -4-羟基- L -脯氨酸, BioXtra, ≥99.0% (NT)
InChI key
PMMYEEVYMWASQN-DMTCNVIQSA-N
InChI
1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4+/m1/s1
SMILES string
O[C@H]1CN[C@@H](C1)C(O)=O
product line
BioXtra
assay
≥99.0% (NT)
form
solid
optical activity
[α]20/D −76.0±1.5°, c = 5% in H2O
impurities
≤0.3% foreign amino acids
ign. residue
≤0.1% (as SO4)
loss
≤0.1% loss on drying, 110 °C
color
colorless to white
mp
273 °C (dec.) (lit.)
anion traces
chloride (Cl-): ≤100 mg/kg, sulfate (SO42-): ≤100 mg/kg
cation traces
Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, NH4+: ≤100 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg
application(s)
peptide synthesis
Quality Level
正在寻找类似产品? 访问 产品对比指南
Biochem/physiol Actions
反式-4-羟基-L-脯氨酸用于有机合成 depsilairdin 类似物、多药耐药 P-糖蛋白的非竞争性拟肽抑制剂和 3-鸟嘌呤基-5-羟甲基-2-吡咯烷酮 (4) 或 3-腺嘌呤基-5-羟甲基-2-吡咯烷酮 (5) 核苷类似物。
反式-4-羟基-L-脯氨酸被用作合成 (-)-secrinine 的起始原料;用于脯氨醇为基础的核苷酸类似物的合成,其中N-磷甲基基团连接脯氨醇环的氮原子,以及用于抗肿瘤抗生素 MPC1001 的 ABC 环系统的不对称合成中。
Other Notes
动物结构蛋白(如胶原和弹性蛋白)的天然成分。
羟脯氨酸降解的酶和中间体
存储类别
11 - Combustible Solids
wgk
WGK 1
ppe
Eyeshields, Gloves, type N95 (US)
E. Adams
Methods in Enzymology, 17B, 266-266 (1971)
Jacob Kofoed et al.
Chemical communications (Cambridge, England), (14)(14), 1482-1484 (2006-04-01)
The aldol reaction of acetone with aldehydes in aqueous medium under catalysis by zinc-proline (Zn(L-Pro)2) and secondary amines such as proline, (2S,4R)-4-hydroxyproline (Hyp) and (S)-(+)-1-(2-pyrrolidinomethyl)pyrrolidine (PMP) is shown to proceed by an enamine mechanism, as evidenced by reductive trapping of
Shahrzad Hosseininia et al.
BMC musculoskeletal disorders, 14, 18-18 (2013-01-11)
It remains to be shown whether OA shares molecular similarities between different joints in humans. This study provides evidence for similarities in cartilage molecular damage in osteoarthritic (OA) joints. Articular cartilage from osteoarthritic hip joints were analysed and compared to
Ville V Meretoja et al.
Biomaterials, 34(17), 4266-4273 (2013-03-16)
In this work, we investigated the effects of lowered oxygen tension (20% and 5% O2) on the chondrogenesis and hypertrophy of articular chondrocytes (ACs), mesenchymal stem cells (MSCs) and their co-cultures with a 30:70 AC:MSC ratio. Cells were cultured for
Hsuan-Shu Lee et al.
Journal of gastroenterology and hepatology, 20(7), 1109-1114 (2005-06-16)
Needle liver biopsy is essential for the diagnosis of liver fibrosis and cirrhosis. However, sampling variability has been reported by semiquantitative methods. The aim of the present study was to investigate quantitatively the sampling variability of needle liver biopsy on
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持