59815
1-（4-异硫氰苄基）乙烯基二胺-N,N,N′,N′-四乙酸
~90% (HPLC)
别名:
异硫氰苄基-EDTA
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关于此项目
经验公式（希尔记法）:
C18H21N3O8S
化学文摘社编号:
分子量:
439.44
UNSPSC Code:
12352106
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
8363400
产品名称
1-（4-异硫氰苄基）乙烯基二胺-N,N,N′,N′-四乙酸, ~90% (HPLC)
InChI
1S/C18H21N3O8S/c22-15(23)7-20(8-16(24)25)6-14(21(9-17(26)27)10-18(28)29)5-12-1-3-13(4-2-12)19-11-30/h1-4,14H,5-10H2,(H,22,23)(H,24,25)(H,26,27)(H,28,29)
SMILES string
OC(=O)CN(CC(Cc1ccc(cc1)N=C=S)N(CC(O)=O)CC(O)=O)CC(O)=O
InChI key
VHMWJVAFPCGUTJ-UHFFFAOYSA-N
assay
~90% (HPLC)
shipped in
wet ice
storage temp.
−20°C
Quality Level
Application
异硫氰苄基-EDTA 是一种用于生物共轭化学的双功能螯合剂，用于标记含伯胺的分子和蛋白质，优先标记其 N 端。
Other Notes
胺反应性探针，可用于抗体螯合物标记
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
K Shah et al.
Bioconjugate chemistry, 7(3), 283-289 (1996-05-01)
The synthesis of a C-5 modified uridine phosphoramidite which contains a primary amino group protected with Fmoc is described. During cleavage and deprotection of chemically synthesized RNA, the Fmoc protecting group is removed to yield a free amino group at
S V Deshpande et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 31(2), 218-224 (1990-02-01)
The metabolism of radiolabeled antibodies is important for radioimmunoimaging and therapy. The loss of indium-111 (111In) from the chelate can pose problems in imaging and increases the radiation dose to normal tissues. We have evaluated the loss in vivo of
Z Yao et al.
Nuclear medicine and biology, 22(2), 199-203 (1995-02-01)
Tn antigen is a glycosylated tumor associated antigen and a murine monoclonal antibody, MLS128, has been identified to react with it. The potential of MLS128 for the radioimmunoimaging of colorectal cancer was studied. MLS128 was labeled with radioiodine by the
T M Rana et al.
Bioconjugate chemistry, 1(5), 357-362 (1990-09-01)
Conjugates of monoclonal antibodies with drugs, toxins, radionuclides, and other agents are in widespread use in therapeutic trials and as clinical research tools. The characterization of these immunoconjugates generally does not include determining the individual sites at which such agents
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