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Merck
CN

61793

2-酮-D-葡萄糖

≥98.0% (TLC)

别名:

D-葡萄糖醛酮

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关于此项目

经验公式(希尔记法):
C6H10O6
化学文摘社编号:
分子量:
178.14
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352201
MDL number:
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产品名称

2-酮-D-葡萄糖, ≥98.0% (TLC)

InChI

1S/C6H10O6/c7-1-3(9)5(11)6(12)4(10)2-8/h1,4-6,8,10-12H,2H2/t4-,5-,6-/m1/s1

SMILES string

OC[C@@H](O)[C@@H](O)[C@H](O)C(=O)C=O

InChI key

DCNMIDLYWOTSGK-HSUXUTPPSA-N

assay

≥98.0% (TLC)

form

solid

color

white to beige

storage temp.

2-8°C

Quality Level

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Application

2-酮基-D-葡萄糖(D-葡萄糖酮)是导致抗生素cortalcerone的次级代谢途径的关键中间体。 D-葡萄糖酮是一种底物,可用于识别、区分和表征己糖激酶。

Biochem/physiol Actions

2-酮基-D-葡萄糖是次级代谢途径的关键中间体,导致β抗生素吡喃酮cortalcerone。这种抗生素能保护真菌免受细菌的侵害。吡喃糖2氧化酶对d-葡萄糖的酶促氧化产生2-酮基-D-葡萄糖,被认为是稀有糖。

Other Notes

为了全面了解我们针对客户研究提供的各种单糖产品,建议您访问我们的碳水化合物分类页面。

Packaging

无底玻璃瓶。内含物装在插入的融合锥内。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Stefan Freimund et al.
Carbohydrate research, 339(2), 217-220 (2003-12-31)
The composition of the 2-keto aldoses D-glucosone (1), 6-deoxy-D-glucosone (2), D-allosone (3), and D-galactosone (4) in organic solvents has been determined using NMR spectroscopy. Whereas these keto aldoses form mixtures with up to 15 different isomers in water, the number
Wenhui Zhang et al.
Journal of the American Chemical Society, 134(28), 11511-11524 (2012-06-02)
Pathways in the degradation of the C(6) 1,2-dicarbonyl sugar (osone) D-glucosone 2 (D-arabino-hexos-2-ulose) in aqueous phosphate buffer at pH 7.5 and 37 °C have been investigated by (13)C and (1)H NMR spectroscopy with the use of singly and doubly (13)C-labeled
A Araki
Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 34(9), 716-720 (1998-02-12)
Increased oxidative stress in diabetes mellitus has been implicated in the pathogenesis of diabetic complications. Both an increase in reactive oxygen free radical species (ROS) and a decrease in the antioxidant defense mechanism lead to the increase in oxidative stress
Kunchala Rungsrisuriyachai et al.
Archives of biochemistry and biophysics, 483(1), 10-15 (2009-01-17)
The flavin-dependent pyranose 2-oxidase catalyzes the oxidation of d-glucose and other pyranoses at the C2 atom to yield 2-keto-sugars and hydrogen peroxide. Here, the steady-state kinetic mechanism of the enzyme from Trametes ochracea was investigated as a function of pH.
Stefan Mittelmaier et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 878(11-12), 877-882 (2010-03-02)
Glucose degradation products (GDPs) formed during heat sterilization of peritoneal dialysis (PD) fluids exert cytotoxic effects and promote the formation of advanced glycation end-products in the peritoneal cavity. As a result, long-term application of continuous ambulatory peritoneal dialysis is limited.

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