Merck
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文件

67060

Sigma-Aldrich

甲基绿

zinc chloride salt, for microscopy (Bact., Bot., Hist.)

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别名:
乙基绿
线性分子式:
C27H35BrClN3 · ZnCl2
CAS号:
7114-03-6
分子量:
653.24
颜色索引号:
42590
Beilstein:
3914106
EC 号:
230-415-4
MDL编号:
MFCD00151094
PubChem化学物质编号:
329760277
NACRES:
NA.47

等级

for microscopy (Bact., Bot., Hist.)

质量水平

200

形式

powder

pH值（酸碱度）

0.2-1.8, yellow to blue

mp

>300 °C (lit.)

溶解性

water: 0.01 g/10 mL, blue to very deep blue

εmax

≥900 at 624-634 nm in water

应用

diagnostic assay manufacturing
hematology
histology

储存温度

room temp

SMILES字符串

[Cl-].[Br-].Cl[Zn]Cl.CC[N+](C)(C)c1ccc(cc1)\C(c2ccc(cc2)N(C)C)=C3/C=C\C(C=C3)=[N+](\C)C

InChI

1S/C27H35N3.BrH.3ClH.Zn/c1-8-30(6,7)26-19-13-23(14-20-26)27(21-9-15-24(16-10-21)28(2)3)22-11-17-25(18-12-22)29(4)5;;;;;/h9-20H,8H2,1-7H3;4*1H;/q+2;;;;;+2/p-4

InChI key

RRKSQWOQZFIQKW-UHFFFAOYSA-J

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相关类别

应用

Methyl green has been used in the histological staining of ovaries. It has also been used as a counterstain in various cells.

生化/生理作用

Marker dye for DNA in acid and neutral media.
Methyl green is mainly used as a DNA stain in histochemistry. At low concentrations it binds selectively to AT-rich regions of native DNA. However, at high concentrations it is present at all available DNA sites.

分析说明

Material may be a mixture of monobromo-monochloro and dichloro ZnCl2 salts.

警示用语：

Danger

危险声明

H314 - H335 - H411

危险分类

Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1B - STOT SE 3

靶器官

Respiratory system

储存分类代码

8A - Combustible, corrosive hazardous materials

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

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Evaluation of apoptosis as a mechanism of follicular cell atresia in the ovaries of cattle (bos indicus) and buffalo (bubalus bubalis) fetuses.
Santos SSD, et al.
Animal Reproduction, 10, 55-61 (2013)
K R Fox et al.
European journal of histochemistry : EJH, 36(3), 263-270 (1992-01-01)
Methyl green has long been used as a DNA stain in histochemistry. The sequence selective binding of the cationic triphenylmethane dyes methyl green, crystal violet and Malachite green to DNA was investigated by DNAase 1 and micrococcal nuclease footprinting. At
Monocyte chemoattractant protein-1 in human atheromatous plaques.
Nelken NA, et al.
The Journal of Clinical Investigation, 88, 1121-1121 (1991)
Paxton M Moon et al.
Journal of molecular medicine (Berlin, Germany), 93(8), 845-856 (2015-07-04)
Osteoarthritis (OA) is a highly prevalent, disabling joint disease with no existing therapies to slow or halt its progression. Cartilage degeneration hallmarks OA pathogenesis, and pannexin 3 (Panx3), a member of a novel family of channel proteins, is upregulated during
Nasim Shweke et al.
The American journal of pathology, 173(3), 631-642 (2008-08-09)
Renal fibrosis is defined by the exaggerated accumulation of extracellular matrix proteins. Tissue transglutaminase (TG2) modifies the stability of extracellular matrix proteins and renders the extracellular matrix resistant to degradation. In addition, TG2 also activates transforming growth factor-beta (TGF-beta). We
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