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关于此项目
经验公式(希尔记法):
C27H32O14
化学文摘社编号:
分子量:
580.53
UNSPSC Code:
12352201
NACRES:
NA.47
PubChem Substance ID:
EC Number:
233-566-4
Beilstein/REAXYS Number:
102012
MDL number:
Quality Level
assay
≥95% (HPLC)
form
powder
optical activity
[α]20/D −80±10°, c = 1% in ethanol
mp
83 °C ((181 °F ))
solubility
ethanol: o.1 g/10 mL, clear to hazy, colorless to light greenish-yellow
SMILES string
C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2Oc3cc(O)c4C(=O)CC(Oc4c3)c5ccc(O)cc5)[C@H](O)[C@H](O)[C@H]1O
InChI
1S/C27H32O14/c1-10-20(32)22(34)24(36)26(37-10)41-25-23(35)21(33)18(9-28)40-27(25)38-13-6-14(30)19-15(31)8-16(39-17(19)7-13)11-2-4-12(29)5-3-11/h2-7,10,16,18,20-30,32-36H,8-9H2,1H3/t10-,16?,18+,20-,21+,22+,23-,24+,25+,26-,27+/m0/s1
InChI key
DFPMSGMNTNDNHN-JJLSSNRUSA-N
Application
柚皮苷用于:
- 作为苦味剂,比较 果蝇 幼虫和成虫的行为反应(2)
- 研究其抗炎特性,确定其对髓核(NP)细胞的作用(3)
- 确定其对骨代谢的影响,如成骨分化、抑制破骨细胞形成(4)。
Biochem/physiol Actions
柚皮苷可以与信号分子相互作用,调节信号通路。具有抗炎和抗癌活性。它还对氧化应激、骨骼再生、遗传损伤、代谢综合征和中枢神经系统(CNS)疾病具有药理作用。
柚皮苷是葡萄柚和其他柑橘类水果中的黄酮类化合物,可强效抑制肠道有机阴离子转运多肽 1A2 (OATP1A2)。因此,葡萄柚汁可降低同时服用的许多药物的生物利用度。
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存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Liquid-liquid extraction (LLE) can be an effective strategy for the purification of polyphenols from a fermentation broth. However, solvents need to be chosen to ensure high extraction capacity and selectivity. For that purpose, a systematic study is here presented, where
Luís F Mendes et al.
Scientific reports, 9(1), 14906-14906 (2019-10-19)
The ability of flavonoids to attenuate macrophage pro-inflammatory activity and to promote macrophage-mediated resolution of inflammation is still poorly understood at the biochemical level. In this study, we have employed NMR metabolomics to assess how therapeutically promising flavonoids (quercetin, naringenin
Therapeutic potential of naringin: an overview
Chen R, et al.
Pharmaceutical biology, 54(12), 3203-3210 (2016)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 71162-25G | 04061835521456 |
| 71162-100G | 04061832843698 |