72485
尼罗红
suitable for microscopy
别名:
尼罗红
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关于此项目
经验公式（希尔记法）:
C20H18N2O2
化学文摘社编号:
分子量:
318.37
UNSPSC Code:
12171500
NACRES:
NA.32
PubChem Substance ID:
EC Number:
230-966-0
Beilstein/REAXYS Number:
279110
MDL number:
InChI key
VOFUROIFQGPCGE-UHFFFAOYSA-N
InChI
1S/C20H18N2O2/c1-3-22(4-2)13-9-10-16-18(11-13)24-19-12-17(23)14-7-5-6-8-15(14)20(19)21-16/h5-12H,3-4H2,1-2H3
SMILES string
CCN(CC)c1ccc2N=C3C(Oc2c1)=CC(=O)c4ccccc34
form
crystals
Quality Level
mol wt
318.37 g/mol
color
brown to very dark brown, red to very dark red
mp
203-205 °C (lit.)
solubility
methanol: 0.01 g/10 mL (red to very dark red)
λmax
553 nm
suitability
suitable for microscopy
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General description
尼罗红是一种苯氧嗪染料。它是一种重要的染色剂，可用于检测细胞内脂滴 和蛋白质。尼罗红可检测溶酶体和溶酶体相关的细胞器，例如秀丽隐杆线虫肠道细胞中的肠道颗粒。它表现出强烈的荧光增强作用，可用于对SDS（十二烷基硫酸钠）凝胶进行染色。
Application
尼罗红已被用于：
- 通过共聚焦扫描激光显微镜（CSLM）作为脂肪染色的荧光染料
- 标记纳米粒子（NPs）
- 用于脂质分析
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Biomacromolecules, 8(11), 3540-3547 (2007)
Labeling nanoparticles: Dye leakage and altered cellular uptake
Snipstad S, et al.
Cytometry. Part A : the Journal of the International Society For Analytical Cytology, 91(8), 760-766 (2017)
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Steinberg TH
Methods in Enzymology, 463, 541-563 (2009)
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Polyphenols in Human Health and Disease, 779-784 (2014)
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