生物来源
goat
偶联物
agarose conjugate
抗体形式
affinity isolated antibody
抗体产品类型
secondary antibodies
克隆
polyclonal
表单
PBS suspension
种属反应性
human
请勿与下列物质发生反应
rat, mouse
容量
3-4 mg/mL binding capacity (human IgA)
储存温度
2-8°C
靶向翻译后修饰
unmodified
一般描述
IgA抗体在粘膜免疫中起着至关重要的作用。它可以结合免疫原/病原体以限制其进入粘膜。抗人IgA（α-链特异性）产品可提高对人IgA的敏感性，而不会与其他物质发生交叉反应。由于与小鼠或大鼠的物种间交叉反应极低，使其适用于筛选由包含小鼠或大鼠免疫球蛋白的杂交瘤细胞产生的抗体。
结合能力：1 mL抗体可结合3-4 mg人IgA。 洗脱能力为2-4 mg/mL。
免疫原
人艾巴氏病毒转化细胞系产生的 IgA。
应用
山羊抗人IgA（α-链特异性）-琼脂糖抗体可用于亲和色谱和定量酶联免疫吸附测定（ELISA）。
用连接琼脂糖的抗人 IgA 抗体进行亲和层析，从 2E9IgA1 转染细胞中纯化蛋白。
外形
0.01 M 磷酸盐缓冲盐水（pH 7.4）混悬液，含 15 mM 叠氮化钠
免责声明
除非我们的目录或随附于产品的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
此项目有
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Poor ex vivo induction of T-cell responses to idiotype or tumor cell lysate-pulsed autologous dendritic cells in advanced pre-treated multiple myeloma
Garderet L, et al.
Leukemia & Lymphoma, 47(7), 1340-1347 (2006)
Yuanyi Yue et al.
Frontiers in immunology, 12, 758040-758040 (2022-02-11)
The tumor microenvironment (TME) plays an important role in the pathogenesis of many cancers. We aimed to screen the TME-related hub genes of colorectal adenoma (CRAD) and identify possible prognostic biomarkers. The gene expression profiles and clinical data of 464
Florian Erger et al.
Proceedings of the National Academy of Sciences of the United States of America, 120(22), e2211087120-e2211087120 (2023-05-22)
Mutations in genes encoding molecular chaperones can lead to chaperonopathies, but none have so far been identified causing congenital disorders of glycosylation. Here we identified two maternal half-brothers with a novel chaperonopathy, causing impaired protein O-glycosylation. The patients have a
M Kristen Demoruelle et al.
Arthritis research & therapy, 23(1), 163-163 (2021-06-08)
Mucosal sites are hypothesized to play a role in the development of rheumatoid arthritis (RA). Since serum anti-peptidylarginine deiminase (PAD)4 antibodies, including a subset that cross-react with PAD3 (PAD3/4), are specific for RA and associate with severe disease, we sought
Yasuyuki Matsumoto et al.
Science advances, 8(43), eabm8783-eabm8783 (2022-10-29)
The underlying pathology of immunoglobulin A (IgA) nephropathy (IgAN), the most common glomerulonephritis worldwide, is driven by the deposition of immune complexes containing galactose-deficient IgA1 [Tn(+)IgA1] in the glomerular mesangium. Here, we report that novel anti-Tn circulating immune complexes (anti-Tn
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