A2795
N-乙酰-d-半乳糖胺
≥98% (HPLC)
别名:
2-乙酰氨基-2-脱氧-D-半乳糖, D-GalNAc, N-乙酰半乳糖胺
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关于此项目
经验公式（希尔记法）:
C8H15NO6
化学文摘社编号:
分子量:
221.21
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
EC Number:
217-321-9
Beilstein/REAXYS Number:
2331340
MDL number:
Quality Level
assay
≥98% (HPLC)
form
powder
technique(s)
HPLC: suitable
color
white
mp
160 °C
solubility
water: 50 mg/mL, clear, colorless
storage temp.
2-8°C
SMILES string
CC(=O)N[C@H]1C(O)O[C@H](CO)[C@H](O)[C@@H]1O
InChI
1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5-,6+,7-,8?/m1/s1
InChI key
OVRNDRQMDRJTHS-KEWYIRBNSA-N
General description
N-乙酰-D-半乳糖胺 (GalNAc) 是一种氨基糖，是许多 O-连接和N-连接聚糖结构的组成部分。作为尿苷二磷酸 (UDP)-GalNAc，GalNAc是许多丝氨酸和苏氨酸残基蛋白质糖基化的初始O连接糖。
Application
N-乙酰-D-半乳糖胺已用于：
- 用作双花扁豆凝集素 (DBA) 半抗原糖，用于凝集素珠结合测定
- 通过凝集素印迹抑制评估凝集素结合的特异性
- 免疫组织化学预吸附紫藤凝集素
N-乙酰-D-半乳糖胺（GalNAc）是一种氨基糖，是许多O-连接和N连接聚糖结构的组分。 作为UDP-GalNAc，GalNAc是许多蛋白质糖基化丝氨酸和苏氨酸残基的起始O-连接糖。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Dezemon Zingue et al.
Scientific reports, 8(1), 6778-6778 (2018-05-02)
Contaminations and fastidiousness of M. ulcerans may have both hamper isolation of strains from environmental sources. We aimed to optimize decontamination and culture of environmental samples to circumvent both limitations. Three strains of M. ulcerans cultured onto Middlebrook 7H10 at
Ju Huang et al.
Molecular therapy. Methods & clinical development, 5, 241-258 (2017-06-13)
Fabry disease is a rare lysosomal storage disorder (LSD). We designed multiple recombinant lentivirus vectors (LVs) and tested their ability to engineer expression of human α-galactosidase A (α-gal A) in transduced Fabry patient CD34
David J Gill et al.
Trends in cell biology, 21(3), 149-158 (2010-12-15)
O-GalNAc glycosylation of proteins confers essential structural, protective and signaling roles in eumetazoans. Addition of O-glycans onto proteins is an extremely complex process that regulates both sites of attachment and the types of oligosaccharides added. Twenty distinct polypeptide GalNAc-transferases (GalNAc-Ts)
Yuki Kuramoto et al.
Journal of molecular and cellular cardiology, 121, 256-265 (2018-07-27)
Fabry disease is an X-linked disease caused by mutations in α-galactosidase A (GLA); these mutations result in the accumulation of its substrates, mainly globotriaosylceramide (Gb3). The accumulation of glycosphingolipids induces pathogenic changes in various organs, including the heart, and Fabry
P Van den Steen et al.
Critical reviews in biochemistry and molecular biology, 33(3), 151-208 (1998-07-23)
The biosynthesis, structures, and functions of O-glycosylation, as a complex posttranslational event, is reviewed and compared for the various types of O-glycans. Mucin-type O-glycosylation is initiated by tissue-specific addition of a GalNAc-residue to a serine or a threonine of the
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| A2795-500MG | 04061835366033 |
| A2795-10MG | 04061832386782 |
| A2795-1G | 04061835366026 |
| A2795-100MG | 04061835366019 |
| A2795-5G | 04061835366040 |
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