A4438
p-Acetamidophenyl β-D-glucuronide sodium salt
>98% (TLC)
别名:
Acetaminophen glucuronide, Paracetamol glucuronide
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关于此项目
线性分子式:
C14H16NO8Na
化学文摘社编号:
分子量:
349.27
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352201
MDL number:
Quality Level
assay
>98% (TLC)
form
powder
impurities
<6% water (Karl Fischer)
color
white to off-white
solubility
water: 25 mg/mL, clear, colorless to light yellow
storage temp.
−20°C
SMILES string
[Na+].CC(=O)Nc1ccc(O[C@@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)C([O-])=O)cc1
InChI
1S/C14H17NO8.Na/c1-6(16)15-7-2-4-8(5-3-7)22-14-11(19)9(17)10(18)12(23-14)13(20)21;/h2-5,9-12,14,17-19H,1H3,(H,15,16)(H,20,21);/q;+1/p-1/t9-,10-,11+,12-,14+;/m0./s1
InChI key
OINXIJJEOMGKPB-CYRSAHDMSA-M
Application
Acetaminophen glucuronide (AA-Gluc) is used as a reference material in procedures that analyse urine and plasma for acetaminophen metabolites to indicate hepatotoxicity.
Other Notes
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.
wgk
WGK 3
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
T Andrew Clayton et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(34), 14728-14733 (2009-08-12)
We provide a demonstration in humans of the principle of pharmacometabonomics by showing a clear connection between an individual's metabolic phenotype, in the form of a predose urinary metabolite profile, and the metabolic fate of a standard dose of the
Scott A Reisman et al.
Toxicological sciences : an official journal of the Society of Toxicology, 109(1), 31-40 (2009-02-28)
Acetaminophen (AA) is a widely used antipyretic drug that causes hepatotoxicity at high doses. Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor that mitigates electrophilic stress from AA by inducing genes, such as NAD(P)H:quinone oxidoreductase 1 (Nqo1)
Carol R Gardner et al.
Toxicological sciences : an official journal of the Society of Toxicology, 125(2), 607-612 (2011-11-04)
Fenbendazole is a broad-spectrum anthelmintic drug widely used to prevent or treat nematode infections in laboratory rodent colonies. Potential interactions between fenbendazole and hepatotoxicants such as acetaminophen are unknown, and this was investigated in this study. Mice were fed a
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| A4438-50MG | 04061832386959 |
| A4438-10MG | 04061832386942 |