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A4737

牛血清白蛋白来源于牛血清

Name: 牛血清白蛋白 来源于牛血清
Brand: SIGMA

lyophilized powder, protease, essentially free, ≥98% (agarose gel electrophoresis)

别名:

BSA, 牛白蛋白, 牛血清白蛋白

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关于此项目

化学文摘社编号:

9048-46-8

UNSPSC Code:

12352202

EC Number:

232-936-2

MDL number:

MFCD00130384

eCl@ss:

32160409

Biological source:

bovine

Assay:

≥98% (agarose gel electrophoresis)

Form:

lyophilized powder

Technique(s):

ligand binding assay: suitable

Impurities:

≤8.0% water (Karl Fischer)

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属性

biological source

bovine

Quality Segment

200

assay

≥98% (agarose gel electrophoresis)

form

lyophilized powder

packaging

poly bottle of

origin

New Zealand origin

technique(s)

ligand binding assay: suitable

impurities

≤8.0% water (Karl Fischer)

pH

4.8-7.5

solubility

H₂O: soluble 50 mg/mL

UniProt accession no.

P02769

foreign activity

protease, essentially free

storage temp.

2-8°C

Gene Information

bovine ... ALB(280717)

说明

General description

The most abundant plasma protein in mammals is albumin. It is produced in the liver and transferred as a non-glycosylated protein into the plasma. This multifunctional protein can bind to ligands.

Application

Bovine serum albumin (BSA) is extensively used for drug delivery since it is widely available, cheap and easily purified, has ligand-binding properties, and is widely accepted in the pharmaceutical industry.

Biochem/physiol Actions

BSA的某些构象和初级序列表位是人类对牛肉和牛奶过敏中的可疑过敏原。

Albumin is the most important circulatory protein involved in the control of Ca²⁺ (and Mg²⁺) levels in mammals.

Preparation Note

血清白蛋白可能也会被称为Fraction V。该命名惯例取自使用冷乙醇沉淀对血清蛋白进行分级的原始Cohn法。血清白蛋白可在采用Cohn′法的第五乙醇分级中发现。从此，有些人便开始使用“Fraction V”这一术语来描述血清白蛋白，无论使用的是什么制备方法。也有人在使用该术语来描述通过乙醇分级方法而纯化得到血清白蛋白，而这种方法是相对于原始的Cohn法一直在得到高度的改良。Sigma-Aldrich生产和分销从各种主要方法纯化得到的血清白蛋白，包括真正的Cohn分级法、改良的乙醇分级方法、热休克和色谱法。更多的纯化步骤包括结晶或木炭过滤。

采用色谱法纯化

Sourced and manufactured in New Zealand

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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c