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Merck
CN

A4737

牛血清白蛋白 来源于牛血清

lyophilized powder, protease, essentially free, ≥98% (agarose gel electrophoresis)

别名:

BSA, 牛白蛋白, 牛血清白蛋白

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化学文摘社编号:
UNSPSC Code:
12352202
EC Number:
232-936-2
MDL number:
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产品名称

牛血清白蛋白 来源于牛血清, lyophilized powder, protease, essentially free, ≥98% (agarose gel electrophoresis)

biological source

bovine

assay

≥98% (agarose gel electrophoresis)

form

lyophilized powder

mol wt

~66 kDa

packaging

poly bottle of

origin

New Zealand origin

technique(s)

ligand binding assay: suitable

impurities

≤8.0% water (Karl Fischer)

pH

4.8-7.5

solubility

H2O: soluble 50 mg/mL

UniProt accession no.

foreign activity

protease, essentially free

storage temp.

2-8°C

Quality Level

Gene Information

bovine ... ALB(280717)

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Biochem/physiol Actions

BSA的某些构象和初级序列表位是人类对牛肉和牛奶过敏中的可疑过敏原。
Albumin is the most important circulatory protein involved in the control of Ca2+ (and Mg2+) levels in mammals.

Preparation Note

血清白蛋白可能也会被称为Fraction V。该命名惯例取自使用冷乙醇沉淀对血清蛋白进行分级的原始Cohn法。 血清白蛋白可在采用Cohn′法的第五乙醇分级中发现。 从此,有些人便开始使用“Fraction V”这一术语来描述血清白蛋白,无论使用的是什么制备方法。 也有人在使用该术语来描述通过乙醇分级方法而纯化得到血清白蛋白,而这种方法是相对于原始的Cohn法一直在得到高度的改良。Sigma-Aldrich生产和分销从各种主要方法纯化得到的血清白蛋白,包括真正的Cohn分级法、改良的乙醇分级方法、热休克和色谱法。 更多的纯化步骤包括结晶或木炭过滤。
采用色谱法纯化
Sourced and manufactured in New Zealand

Application

Bovine serum albumin (BSA) is extensively used for drug delivery since it is widely available, cheap and easily purified, has ligand-binding properties, and is widely accepted in the pharmaceutical industry.

General description

The most abundant plasma protein in mammals is albumin. It is produced in the liver and transferred as a non-glycosylated protein into the plasma. This multifunctional protein can bind to ligands.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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Ting Gong et al.
Biology of reproduction, 95(6), 116-116 (2016-09-30)
Saccharin sodium consumption is considered safe and beneficial, owing to its very intense sweetness without any associated calories, but supporting scientific data remain sparse and controversial. Herein, we demonstrate that dose-response relationships existed with regard to administration of saccharin or
Yuangang Zu et al.
International journal of nanomedicine, 8, 1207-1222 (2013-04-10)
The livertaxis of glycyrrhizic acid-conjugated bovine serum albumin (GL-BSA) has been reported in the literature. Now, in this paper, we describe a novel type of drug-targeted delivery system containing 10-hydroxycamptothecin (HCPT) with liver tumor targeting. First, GL was coupled to
Karolina A Majorek et al.
Molecular immunology, 52(3-4), 174-182 (2012-06-09)
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Use of MULTI-seq lipid-modified oligos, protocol, and troubleshooting guide for PCR Assays and Sequencing applications.

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