A5285
腺苷 5′-二磷酸 单钾盐 二水合物
bacterial, ≥95%, P2Y receptor agonist, powder
别名:
5′-二磷酸腺苷钾盐, ADP
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关于此项目
经验公式（希尔记法）:
C10H14KN5O10P2 · 2H2O
化学文摘社编号:
分子量:
501.32
UNSPSC Code:
41106305
eCl@ss:
32160414
PubChem Substance ID:
NACRES:
NA.77
MDL number:
产品名称
腺苷 5′-二磷酸 单钾盐 二水合物, bacterial, ≥95%, powder
SMILES string
[O-]P(OP(OC[C@H]([C@@H](O)[C@H]1O)O[C@H]1N2C3=C(N=C2)C(N)=NC=N3)(O)=O)(O)=O.[K+]
InChI
1S/C10H15N5O10P2.K/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20);/q;+1/p-1/t4-,6-,7-,10-;/m1./s1
InChI key
ZNCWUOPIJTUALR-MCDZGGTQSA-M
biological source
bacterial
assay
≥95%
form
powder
storage temp.
−20°C
Quality Level
Gene Information
human ... HSP90AA1(3320), P2RY1(5028)
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Application
5′-二磷酸腺苷已被用于研究大鼠脑中细胞外β-烟酰胺腺嘌呤二核苷酸(β-NAD+)的释放、神经元效应和去除。 5′-二磷酸腺苷也被用于比较急性冠状动脉综合征后普拉格雷与氯吡格雷抗血小板治疗的效果。
5′-二磷酸腺苷单钾盐二水合物 (ADP)已用于:
- 滴定以测定渗透性肌纤维中复合物I辅助的呼吸
- 滴定以测定ADP刺激的呼吸动力学
- 制备用于测定线粒体呼吸的ADP溶液
General description
二磷酸腺苷（ADP）是活生物体中能量流动的关键一环。其结构包括连接腺嘌呤的糖骨架，以及连接核糖第五个碳原子的两个磷酸基团。ADP可作为ATP生物合成的前体。 ADP可作为特异性靶向P2Y受体的血小板弱激动剂。但是，ADP在血小板功能中起关键作用，由血小板致密颗粒释放时可增强其它血小板激动剂的作用，并促进血小板聚集体的稳定性。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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