A6608
白蛋白 人
recombinant, expressed in Saccharomyces cerevisiae, aqueous solution, 10% in aqueous buffer, ≥99% (agarose gel electrophoresis)
别名:
rHSA
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关于此项目
经验公式（希尔记法）:
C2936H4624N786O889S41
化学文摘社编号:
分子量:
66471.53
UNSPSC Code:
12352202
eCl@ss:
42010201
NACRES:
NA.25
MDL number:
产品名称
白蛋白 人, recombinant, expressed in Saccharomyces cerevisiae, aqueous solution, 10% in aqueous buffer, ≥99% (agarose gel electrophoresis)
SMILES string
FC(F)(F)C(F)(F)C(F)(F)F
InChI
1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11
InChI key
QYSGYZVSCZSLHT-UHFFFAOYSA-N
biological source
human
recombinant
expressed in Saccharomyces cerevisiae
assay
≥99% (agarose gel electrophoresis)
form
aqueous solution
mol wt
monomer ~67 kDa
concentration
10% in aqueous buffer
technique(s)
cell culture | mammalian: suitable
UniProt accession no.
storage temp.
2-8°C
Quality Level
Gene Information
human ... ALB(213)
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Analysis Note
经过内毒素检测
Application
该重组变异建议用于：吸收、分散、代谢和排泄（ADME）药理学研究；细胞培养；药物递送研究；细胞冻存。
Albumin human has been used:
- to study its adsorption process on model mica surface at pH 3.5 using the atomic force microscopy (AFM) and in situ streaming potential measurements
- to study its proteolytic activities under reducing conditions
- in the medium for stem cell cultivation
Biochem/physiol Actions
白蛋白是可见于动物体液和组织及部分植物种子的一类可溶性单体蛋白。 血清白蛋白可作为类固醇、脂肪酸和甲状腺激素的载体蛋白。 血清白蛋白在调节血液的胶体渗透压方面也至关重要。
Albumin is a binding and transport protein that serves as a protein repository and a carrier for amino acids. Albumin binding dissolves the biomolecules in blood and ensures its effective transport. This also prevents the loss of substance through excretion. Pathological conditions like vasculitis, lymphangiectasia, glomerulonephritis, and hepatic sinusoidal hypertension might result in hypoalbuminemia. This product can be used in the pharmaceutical industry as a drug excipient and to coat medical devices.
Other Notes
更多信息参见人血清白蛋白。
General description
Albumin constitutes 25% of the proteins produced by the liver and is a prominent protein found in the blood. It is a protein of a single polypeptide chain with a thiol group.
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Autoreactivity against Denatured Type III Collagen Is Significantly Decreased in Serum from Patients with Cancer Compared to Healthy Controls.
Jensen, et al.
International Journal of Molecular Sciences, 24 (2023)
Fluid, electrolyte, and acid-base disturbances in liver disease
Fluid, Electrolyte, and Acid-Base Disorders in Small Animal Practice, 456-456 (2011)
Marta Kujda et al.
Colloids and surfaces. B, Biointerfaces, 127, 192-199 (2015-02-14)
Recombinant human serum albumin (rHSA) in monomeric state is widely used in pharmaceutical industry as a drug excipient and for preparing coatings for medical devices. In this work the adsorption process of rHSA on model mica surface at pH 3.5
N A Pham et al.
Cytometry, 41(4), 245-251 (2000-11-21)
Increased mitochondrial generation of reactive oxygen intermediates (ROI) due to defective respiratory chain activity has been implicated in physiological processes such as apoptosis, in the pathogenesis of mitochondrial diseases, and as part of the normal aging process. Established methods addressing
Abnormalities of plasma proteins
Scientific Foundations of Biochemistry in Clinical Practice, 464-494 (1994)
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