Merck
CN

A8292

Sigma-Aldrich

A-α-D-葡萄糖醛酸甲基酯

≥93% (GC)

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别名:
(2,3,4-三-O-乙酰基-α-D-溴代葡萄糖)醛酸甲基酯, 乙酰溴-α-D-葡萄糖酮酸甲基酯, 溴代-2,3,4-三-O-乙酰基-α-D-葡萄糖醛酸甲酯
Empirical Formula (Hill Notation):
C13H17BrO9
CAS号:
分子量:
397.17
Beilstein:
96281
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.25

质量水平

检测方案

≥93% (GC)

形式

powder

旋光性

[α]/D 188 to 198 °, c = 1% (w/v) in ethyl acetate

颜色

white

mp

80-110 °C (lit.)

溶解性

ethyl acetate: 50 mg/mL, clear, colorless to faintly yellow

运输

dry ice

储存温度

−20°C

SMILES string

COC(=O)[C@H]1O[C@H](Br)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O

InChI

1S/C13H17BrO9/c1-5(15)20-8-9(21-6(2)16)11(13(18)19-4)23-12(14)10(8)22-7(3)17/h8-12H,1-4H3/t8-,9-,10+,11-,12-/m0/s1

InChI key

GWTNLHGTLIBHHZ-SVNGYHJRSA-N

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此商品
A1750A7562345482
Acetobromo-α-D-glucose ≥95% (TLC)

Sigma-Aldrich

A1750

Acetobromo-α-D-glucose

Acetobromo-α-D-galactose ≥93% (TLC)

Sigma-Aldrich

A7562

Acetobromo-α-D-galactose

form

powder

form

powder

form

powder

form

liquid

color

white

color

white to off-white

color

white to off-white

color

-

mp

80-110 °C (lit.)

mp

88.5 °C ((191.3 °F ))

mp

-

mp

-

solubility

ethyl acetate: 50 mg/mL, clear, colorless to faintly yellow

solubility

-

solubility

chloroform: soluble 5 mg/mL

solubility

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

-

应用

乙溴-α-D-葡糖醛酸甲酯可用于合成HMR1098-S-葡糖醛酸甲酯,这是一种新型K-ATP阻断剂,正被开发为预防心源性猝死的药物。

其他说明

为了全面了解我们针对客户研究提供的各种单糖产品,建议您访问我们的碳水化合物分类页面。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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Slide 1 of 4

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Katarzyna Choma et al.
Journal of bioenergetics and biomembranes, 41(4), 323-334 (2009-10-13)
Mitochondrial potassium channels in the brain have been suggested to have an important role in neuroprotection. The single channel activity of mitochondrial potassium channels was measured after reconstitution of the purified inner membrane from rat brain mitochondria into a planar
Brian T Ethell et al.
Drug metabolism and disposition: the biological fate of chemicals, 31(8), 1027-1034 (2003-07-18)
HMR1098, a novel KATP-blocking agent, is metabolized to form an S-glucuronide in rat and dog bile. Synthesis of the S-glucuronide metabolite was studied in human liver and kidney microsomes. Recombinant UPD-glucuronosyltransferases (UGTs) were screened for activity, and kinetic analysis was
John C Quindry et al.
American journal of physiology. Heart and circulatory physiology, 299(1), H175-H183 (2010-05-04)
The mechanisms responsible for anti-arrhythmic protection during ischemia-reperfusion (IR) in exercised hearts are not fully understood. The purpose of this investigation was to examine whether the ATP-sensitive potassium channels in the mitochondria (mito K(ATP)) and sarcolemma (sarc K(ATP)) provide anti-arrhythmic

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