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Merck
CN

A8843

AM580

≥98% (HPLC), RAR-α agonist, solid

别名:

4- [(5,6,7,8-四氢-5,5,8,8-四甲基-2-萘基)甲酰胺基] 苯甲酸

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关于此项目

经验公式(希尔记法):
C22H25NO3
化学文摘社编号:
分子量:
351.44
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
Quality level:
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产品名称

AM580, ≥98% (HPLC)

SMILES string

CC1(C)CCC(C)(C)c2cc(ccc12)C(=O)Nc3ccc(cc3)C(O)=O

InChI key

SZWKGOZKRMMLAJ-UHFFFAOYSA-N

InChI

1S/C22H25NO3/c1-21(2)11-12-22(3,4)18-13-15(7-10-17(18)21)19(24)23-16-8-5-14(6-9-16)20(25)26/h5-10,13H,11-12H2,1-4H3,(H,23,24)(H,25,26)

assay

≥98% (HPLC)

form

solid

storage temp.

−20°C

Quality Level

Gene Information

Application

类视黄醇衍生物用于白血病-视黄酸受体 (PHL-RAR) 细胞系分化的基因表达研究。

General description

AM580是视黄苯甲酸衍生物和RAR-α(视黄酸受体-α)激动剂。它刺激 NB4 早幼粒细胞白血病细胞系和 APL(急性早幼粒细胞白血病)原始细胞中粒细胞的成熟。AM580 抑制子宫内膜癌细胞增殖。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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