A8843
AM580
≥98% (HPLC), RAR-α agonist, solid
别名:
4- [（5,6,7,8-四氢-5,5,8,8-四甲基-2-萘基）甲酰胺基] 苯甲酸
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关于此项目
经验公式（希尔记法）:
C22H25NO3
化学文摘社编号:
分子量:
351.44
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
产品名称
AM580, ≥98% (HPLC)
质量水平
方案
≥98% (HPLC)
表单
solid
储存温度
−20°C
SMILES字符串
CC1(C)CCC(C)(C)c2cc(ccc12)C(=O)Nc3ccc(cc3)C(O)=O
InChI
1S/C22H25NO3/c1-21(2)11-12-22(3,4)18-13-15(7-10-17(18)21)19(24)23-16-8-5-14(6-9-16)20(25)26/h5-10,13H,11-12H2,1-4H3,(H,23,24)(H,25,26)
InChI key
SZWKGOZKRMMLAJ-UHFFFAOYSA-N
基因信息
human ... RARA(5914), RARB(5915)
一般描述
AM580是视黄苯甲酸衍生物和RAR-α（视黄酸受体-α）激动剂。它刺激 NB4 早幼粒细胞白血病细胞系和 APL（急性早幼粒细胞白血病）原始细胞中粒细胞的成熟。AM580 抑制子宫内膜癌细胞增殖。
应用
类视黄醇衍生物用于白血病-视黄酸受体 (PHL-RAR) 细胞系分化的基因表达研究。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
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