A9605
AC-93253
≥98% (HPLC)
别名:
2-[3-(1,3-Dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)-1-propenyl]-3-ethyl-benzothiazolium iodide
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关于此项目
经验公式(希尔记法):
C23H25N2SI
化学文摘社编号:
分子量:
488.43
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
方案
≥98% (HPLC)
表单
solid
储存条件
desiccated
颜色
dark purple
溶解性
DMSO: >10 mg/mL
H2O: insoluble
储存温度
2-8°C
SMILES字符串
[I-].CC[n+]1c(\C=C\C=C2\N(C)c3ccccc3C2(C)C)sc4ccccc14
InChI
1S/C23H25N2S.HI/c1-5-25-19-13-8-9-14-20(19)26-22(25)16-10-15-21-23(2,3)17-11-6-7-12-18(17)24(21)4;/h6-16H,5H2,1-4H3;1H/q+1;/p-1
InChI key
TWBRXRGFFUATNI-UHFFFAOYSA-M
生化/生理作用
AC-93253 is a potent, cell permeable, subtype selective RAR (RARα) agonist. EC50 = 6.3 μM. AC-93253 has high selectivity; 89% for RARα vs 67% for RARβ1, 35% for RARβ2, and 11% for RARγ.
Potent, cell permeable, subtype selective RAR (RARα) agonist.
特点和优势
This compound is featured on the Nuclear Receptors (Non-Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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