biological source
goat
conjugate
peroxidase conjugate
antibody form
IgG fraction of antiserum
antibody product type
secondary antibodies
clone
polyclonal
form
buffered aqueous solution
technique(s)
direct ELISA: 1:2,000, dot blot: 1:10,000 (chemiluminescent)
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
General description
免疫球蛋白E(IgE)属于免疫球蛋白家族,由恒定(C)区中的艾普西隆(epsilon)(ε)重链组成。 IgE是在恒定区有额外结构域的单体结构。
IgE是糖蛋白抗体,可调节过敏和感染产生的免疫应答。这些免疫球蛋白参与介导I型超敏反应 。IgE水平升高与高IgE综合征和过敏性哮喘有关。抗人IgE ε-链特异性过氧化物酶抗体与人IgE结合,也可抗人IgG、Bence Jones蛋白 κ 和 λ 骨髓瘤蛋白。
Immunogen
从人骨髓瘤血清中纯化的 IgE
Application
山羊抗人IgE(ε-链特异性)-过氧化物酶抗体可用于IgE免疫印迹和蛋白印迹法分析IgE结合效率。
Physical form
溶于0.01M磷酸盐缓冲液,pH 7.4,含有0.05% MIT
Preparation Note
采用 Avrameas,S.等人 Scand J. Immunol .,8,增刊,7, 7 (1978) 描述的两步戊二醛法制备。
Disclaimer
除非我们的产品目录或产品随附的其他公司文件中另有说明,否则我们的产品仅用于研究用途,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、体外或体内治疗用途或任何类型的人类或动物消费或应用。
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signalword
Danger
hcodes
Hazard Classifications
Resp. Sens. 1 - Skin Sens. 1
存储类别
12 - Non Combustible Liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
低风险生物材料
常规特殊物品
此项目有
Effects of different thermal processing methods on the structure and allergenicity of peanut allergen Ara h 1
Tian Y, et al.
Food Science & Nutrition, 6(6), 1706-1714 (2018)
De-Wang Wang et al.
Molecular medicine reports, 17(1), 394-399 (2017-11-09)
Platanus acerifolia is one of the major sources of outdoor allergens to humans, and can induce allergic asthma, rhinitis, dermatitis and other allergic diseases. Pla a 2 is a polygalacturonase and represents the major allergen identified in P. acerifolia pollen. The aim
Nataly Cancelliere et al.
Biomedical reports, 12(6), 326-332 (2020-04-30)
Parietaria judaica and P. officinalis are the two most common subspecies of the Parietaria genus. P. judaica and P. officinalis have exhibited cross-reactivity in previous studies. P. judaica pollen is the main cause of allergy in the Mediterranean area. It
Ayca Kiykim et al.
International archives of allergy and immunology, 178(1), 1-9 (2018-11-08)
About 65-80% of children with IgE-mediated cow's milk allergy (CMA) can tolerate extensively heated milk. We have invested in the mass fabrication of a test product containing milk protein baked at 180°C for 30 min (SUTMEK-milk) and a milk-free placebo
Yang Tian et al.
Food science & nutrition, 6(6), 1706-1714 (2018-09-28)
Boiling and frying can alter the structure of peanut allergens and therefore change the IgE-binding capacity of the Ara h 1. In this research, we aim to clarify the connections between structural changes and the allergenicity alteration, and recommend an
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抗体的质量决定了整个免疫检测的成败, 是在选择抗体时首选的考虑因素。基于Sigma®、Chemicon®、Upstate®、Mil l ipore®、 Calbiochem®和Novagen®等子品牌的强强联合,默克在创新的 免疫原设计、免疫、挑选、筛选和验证等方面有着数十年的经验, 创造出许多被广泛使用的抗体,如4G10,Neun,组蛋白修饰等抗 体都是相关领域的“金标”抗体。 我们的技术和科研背景使默克成为高质量抗体的主要设计者和生产 者,而不仅仅是经销商。毋庸置疑,我们的每个小瓶中的抗体都包 含着大量的科学研究成果。
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
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