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AMAB90569

单克隆抗-NLRP3 小鼠抗

Name: 单克隆抗-NLRP3 小鼠抗
Brand: SIGMA

Prestige Antibodies^® Powered by Atlas Antibodies, clone CL0210, purified immunoglobulin, buffered aqueous glycerol solution

别名:

抗-AGTAVPRL, 抗-AII, 抗-AVP, 抗-C1orf7, 抗-CIAS1, 抗-CLR1.1, 抗-FCAS, 抗-FCU, 抗-MWS, 抗-NALP3, 抗-PYPAF1

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关于此项目

NACRES:

NA.43

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

CL0210, monoclonal

Application:

Citations:

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属性

biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

CL0210, monoclonal

product line

Prestige Antibodies^® Powered by Atlas Antibodies

form

buffered aqueous glycerol solution

species reactivity

human

concentration

1 mg/mL

technique(s)

immunoblotting: 1 μg/mL, immunofluorescence: 2-10 μg/mL (Fixation/Permeabilization: PFA/Triton X-100)

pH range

7.2-7.4

isotype

IgG1

UniProt accession no.

Q96P20

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... NLRP3(114548)

说明

Immunogen

NLR 家族，pyrin 结构域包含 3

Application

所有由 Atlas抗体^®提供支持的 Prestige 抗体均由 Human Protein Atlas（HPA）项目开发和验证。每种抗体都通过针对数百种正常和疾病组织的免疫组织化学进行测试。通过单击图像库链接，可以在人类蛋白质图谱（HPA）站点上查看这些图像。我们还提供Prestige Antibodies^® 抗体的实验方案和其他有用信息。

Features and Benefits

Prestige Antibodies^®是经过高度表征和广泛验证的抗体，同时还有一个优点是其每个靶标的所有可用表征数据都可以通过位于此页面顶部产品名称下方的人类蛋白质图谱门户进行访问。Prestige Antibodies^®对其他蛋白质的独特性和低交叉反应性是通过严密的抗原区域选择、亲和纯化和严格的选择来实现的。每种Prestige 抗体都有相应的Prestige 抗原对照品，可在链接部分找到。

每种Prestige 抗体的检测方法如下：

44种正常人体组织和20种最常见癌症组织的IHC组织阵列。
364个人重组蛋白片段的蛋白阵列。

Physical form

磷酸盐缓冲盐水，pH 7.2，含有40%甘油和0.02%叠氮化钠

Preparation Note

Upon arrival, mix gently and aliquot to avoid repeated freeze-thaw cycles

Legal Information

Prestige Antibodies is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

低风险生物材料

常规特殊物品

此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

2595

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Simultaneous activation of innate and adaptive immunity participates in the development of renal injury in a model of heavy proteinuria.

Viviane Dias Faustino et al.

Bioscience reports, 38(4) (2018-06-20)

Protein overload of proximal tubular cells (PTCs) can promote interstitial injury by unclear mechanisms that may involve activation of innate immunity. We investigated whether prolonged exposure of tubular cells to high protein concentrations stimulates innate immunity, triggering progressive interstitial inflammation

FNDC5 Attenuates Oxidative Stress and NLRP3 Inflammasome Activation in Vascular Smooth Muscle Cells via Activating the AMPK-SIRT1 Signal Pathway.

Bing Zhou et al.

Oxidative medicine and cellular longevity, 2020, 6384803-6384803 (2020-06-09)

Vascular oxidative stress and inflammation play a major role in vascular diseases. This study was aimed at determining the protective roles of fibronectin type III domain-containing 5 (FNDC5) in angiotensin II- (Ang II-) induced vascular oxidative stress and inflammation and

A Role for the Inflammasome in Spontaneous Labor at Term.

Roberto Romero et al.

American journal of reproductive immunology (New York, N.Y. : 1989), 79(6), e12440-e12440 (2016-03-10)

Inflammasomes are signaling platforms that, upon sensing pathogens and sterile stressors, mediate the release of mature forms of interleukin (IL)-1β and IL-18. The aims of this study were to determine (i) the expression of major inflammasome components in the chorioamniotic

全球贸易项目编号

货号	GTIN
AMAB90569-25UL	04061841706434
AMAB90569-100UL	04061833252062