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Merck
CN

AV34717

Sigma-Aldrich

抗TRIM31 兔抗

affinity isolated antibody

别名:

抗含三联基元31(Tripartite motif-containing 31)

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关于此项目

UNSPSC代码:
12352203
NACRES:
NA.41
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生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous solution

分子量

48 kDa

种属反应性

human

浓度

0.5 mg - 1 mg/mL

技术

immunohistochemistry: suitable
western blot: suitable

NCBI登记号

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... TRIM31(11074)

一般描述

TRIM31是一种包含B-box、RING和卷曲螺旋三个锌结合结构域的蛋白质。TRIM31基因的改变与注意力缺陷/多动障碍(ADHD)有关,而蛋白质水平的变化与胃癌和非小细胞肺癌有关。
兔抗TRIM31抗体可识别人、牛和小鼠TRIM31。

免疫原

靶向人TRIM31 N末端区域的合成肽

应用

兔抗TRIM31抗体适用于蛋白印迹(0.5 μg/ml)和IHC(4-8 μg/ml)分析。

生化/生理作用

TRIM31编码三重基序(TRIM)家族的成员。TRIM基序包括三个锌结合结构域,RING、B-box1和B-box2以及卷曲螺旋结构域。该蛋白质定位于细胞质和细胞核。

外形

本品为溶于1x PBS缓冲液的纯化抗体,含 0.09% (w/v) 叠氮化钠和2%蔗糖。

其他说明

位于以下区域内的合成肽: CRESKDHKSHNVSLIEEAAQNYQGQIQEQIQVLQQKEKETVQVKAQGVHR

免责声明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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储存分类代码

10 - Combustible liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Hui Li et al.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 35(6), 5747-5752 (2014-02-26)
The present study aims to investigate expression pattern and biological roles of TRIM31 in human non-small cell lung cancer (NSCLC). We examined TRIM31 expression in 116 NSCLC tissues and 20 corresponding normal lung tissues by immumohistochemistry. We found TRIM31 downregulation
Takeyuki Sugiura
Cell biology international, 35(7), 657-661 (2011-01-15)
TRIM (tripartite motif) family proteins, comprising RING finger, B-box and coiled-coil domains, are involved in various cellular processes including tumour development and antiviral response. One of the family proteins, TRIM31, was originally identified as a gene induced by growth-suppressive retinoid.
Shenglan Zeng et al.
Redox biology, 45, 102058-102058 (2021-07-05)
Tripartite motif (TRIM) 31 has been implicated in diverse biological and pathological conditions. However, whether TRIM31 plays a role in ischemic stroke progression is not clarified. Here we demonstrated that TRIM31 was significantly downregulated in the ischemic brain and the
Thais S Rizzi et al.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 156(2), 145-157 (2011-02-09)
Intelligence is a highly heritable trait for which it has proven difficult to identify the actual genes. In the past decade, five whole-genome linkage scans have suggested genomic regions important to human intelligence; however, so far none of the responsible
Shigao Yang et al.
Science advances, 5(5), eaav7999-eaav7999 (2019-06-01)
The mitochondrial antiviral signaling protein (MAVS) orchestrates host antiviral innate immune response to RNA virus infection. However, how MAVS signaling is controlled to eradicate virus while preventing self-destructive inflammation remains obscure. Here, we show that protein geranylgeranylation, a posttranslational lipid

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