产品名称
抗TRIM31 兔抗, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
48 kDa
species reactivity
human
concentration
0.5 mg - 1 mg/mL
technique(s)
immunohistochemistry: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... TRIM31(11074)
Application
兔抗TRIM31抗体适用于蛋白印迹（0.5 μg/ml）和IHC（4-8 μg/ml）分析。
Biochem/physiol Actions
TRIM31编码三重基序（TRIM）家族的成员。TRIM基序包括三个锌结合结构域，RING、B-box1和B-box2以及卷曲螺旋结构域。该蛋白质定位于细胞质和细胞核。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
TRIM31是一种包含B-box、RING和卷曲螺旋三个锌结合结构域的蛋白质。TRIM31基因的改变与注意力缺陷/多动障碍（ADHD）有关，而蛋白质水平的变化与胃癌和非小细胞肺癌有关。
兔抗TRIM31抗体可识别人、牛和小鼠TRIM31。
兔抗TRIM31抗体可识别人、牛和小鼠TRIM31。
Immunogen
靶向人TRIM31 N末端区域的合成肽
Other Notes
位于以下区域内的合成肽： CRESKDHKSHNVSLIEEAAQNYQGQIQEQIQVLQQKEKETVQVKAQGVHR
Physical form
本品为溶于1x PBS缓冲液的纯化抗体，含 0.09% (w/v) 叠氮化钠和2%蔗糖。
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存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Hui Li et al.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 35(6), 5747-5752 (2014-02-26)
The present study aims to investigate expression pattern and biological roles of TRIM31 in human non-small cell lung cancer (NSCLC). We examined TRIM31 expression in 116 NSCLC tissues and 20 corresponding normal lung tissues by immumohistochemistry. We found TRIM31 downregulation
Shenglan Zeng et al.
Redox biology, 45, 102058-102058 (2021-07-05)
Tripartite motif (TRIM) 31 has been implicated in diverse biological and pathological conditions. However, whether TRIM31 plays a role in ischemic stroke progression is not clarified. Here we demonstrated that TRIM31 was significantly downregulated in the ischemic brain and the
Thais S Rizzi et al.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 156(2), 145-157 (2011-02-09)
Intelligence is a highly heritable trait for which it has proven difficult to identify the actual genes. In the past decade, five whole-genome linkage scans have suggested genomic regions important to human intelligence; however, so far none of the responsible
Takeyuki Sugiura
Cell biology international, 35(7), 657-661 (2011-01-15)
TRIM (tripartite motif) family proteins, comprising RING finger, B-box and coiled-coil domains, are involved in various cellular processes including tumour development and antiviral response. One of the family proteins, TRIM31, was originally identified as a gene induced by growth-suppressive retinoid.
Xiang He et al.
The EMBO journal, 38(14), e100978-e100978 (2019-07-16)
Viral infection triggers the formation of mitochondrial antiviral signaling protein (MAVS) aggregates, which potently promote immune signaling. Autophagy plays an important role in controlling MAVS-mediated antiviral signaling; however, the exact molecular mechanism underlying the targeted autophagic degradation of MAVS remains
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