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Merck
CN

AV48140

Anti-PGK1 (AB1) antibody produced in rabbit

affinity isolated antibody

别名:

Anti-MGC117307, Anti-MGC142128, Anti-MGC8947, Anti-MIG10, Anti-PGKA, Anti-Phosphoglycerate kinase 1

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关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
western blot
Species reactivity:
horse, sheep, bovine, rat, human, guinea pig, dog, mouse, rabbit
Citations:
3
Technique(s):
western blot: suitable
Uniprot accession no.:
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产品名称

Anti-PGK1 (AB1) antibody produced in rabbit, affinity isolated antibody

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

44 kDa

species reactivity

horse, sheep, bovine, rat, human, guinea pig, dog, mouse, rabbit

concentration

0.5 mg - 1 mg/mL

technique(s)

western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

human ... PGK1(5230)

Application

Rabbit Anti-PGK1 antibody has been used as a loading control in immunoblotting assays. The product is suitable at a concentration of 0.5μg/ml for western blots.

Biochem/physiol Actions

PGK1 is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The protein may also act as a cofactor for polymerase alpha.The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. A pseudogene of this gene has been found on the X-chromosome and another on chromosome 19. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. A pseudogene of this gene has been found on the X-chromosome and another on chromosome 19. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Phosphoglycerate kinase 1 (PGK1) is an enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate during glycolysis. PGK1 expression has been correlated to CXCR4 expression, survival and bone marrow metastasis in neuroblastoma patients.
Rabbit Anti-PGK1 antibody recognizes bovine, human, mouse, rat, and canine PGK1.

Immunogen

Synthetic peptide directed towards the N terminal region of human PGK1

Other Notes

Synthetic peptide located within the following region: PEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFR

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

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存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

常规特殊物品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Helen M Ameis et al.
PloS one, 8(12), e83701-e83701 (2014-01-01)
A close relationship between phosphoglycerate kinase 1 (PGK1) and the CXCR4/SDF1 axis (chemokine receptor 4/stromal cell derived factor 1) has been shown for several cancers. However, the role of PGK1 has not been investigated for neuroblastoma, and PGK1 might be
Alice Y Wang et al.
Molecular and cellular biology, 31(18), 3871-3884 (2011-07-28)
The incorporation of histone variants into nucleosomes represents one way of altering the chromatin structure to accommodate diverse functions. Histone variant H2A.Z has specific roles in gene regulation, heterochromatin boundary formation, and genomic integrity. The precise features required for H2A.Z
Caiyan Huang et al.
Meat science, 199, 109126-109126 (2023-02-04)
The aim of this study was to identify the potential indicators of lamb meat quality by TMT and PRM-based proteomics combined with bioinformatic analysis. Lamb muscles were divided into three different meat quality groups (high, middle and low) according to

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