AV54274
抗-ATG10 兔抗
affinity isolated antibody
别名:
抗-APG10, 抗-APG10L, 抗-ATG10自噬相关的10同源物 （酿酒酵母）, 抗-DKFZP586I0418, 抗-FLJ13954, 抗-Pp12616
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
western blot
Species reactivity:
mouse, rat, human
Citations:
4
Technique(s):
western blot: suitable
Uniprot accession no.:
产品名称
抗-ATG10 兔抗, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
25 kDa
species reactivity
mouse, rat, human
concentration
0.5 mg - 1 mg/mL
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... ATG10(83734)
Application
兔产生的抗-ATG10抗体在1μg/mL浓度下适用于蛋白质印迹。
Biochem/physiol Actions
Atg10是一种E2样酶，可促进添加自噬体形成所必需的泛素化修饰。它催化ATG12与ATG5的结合，这对于ATG8正确定位到自噬前体结构（PAS）至关重要。此外，Atg10在Atg12偶联过程中将LC3的可溶形式修饰为膜结合形式中也起作用。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
ATG10[自噬相关10同源物（酿酒酵母）]或APG10基因编码酵母自噬所必需的蛋白。自噬是一种分解代谢的细胞事件，包括多余或功能失调的细胞成分的细胞死亡，细胞分化和衰老。它对于在氮饥饿下维持氨基酸水平和蛋白合成也至关重要，并且在某些条件下（例如激素刺激和药物治疗）会增强。
Immunogen
靶向人ATG10 C末端区域的合成肽
Other Notes
合成肽位于以下区域内： TPVLKNSQKINKNVNYITSWLSIVGPVVGLNLPLSYAKATSQDERNVP
Physical form
本品为溶于1x PBS缓冲液的纯化抗体，含 0.09% (w/v) 叠氮化钠和2%蔗糖。
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存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
[The nurse; cancerology and radiotherapy].
C Chenal et al.
Revue de l'infirmiere, 26(8), 686-695 (1976-10-01)
Miao-Qing Zhang et al.
Frontiers in immunology, 9, 2176-2176 (2018-10-16)
Autophagy-related 10 (ATG10) is essential for autophagy since it promotes ATG5-ATG12 complex formation. Our previous study found that there are two isoforms of the ATG10 protein, ATG10 (a longer one) and ATG10S, which have identical sequences except an absence of
N Mizushima et al.
Nature, 395(6700), 395-398 (1998-10-06)
Autophagy is a process for the bulk degradation of proteins, in which cytoplasmic components of the cell are enclosed by double-membrane structures known as autophagosomes for delivery to lysosomes or vacuoles for degradation. This process is crucial for survival during
Takahiro Nemoto et al.
The Journal of biological chemistry, 278(41), 39517-39526 (2003-08-02)
Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes/vacuoles. The formation of autophagosomes involves a dynamic rearrangement of the membrane for which two ubiquitin-like modifications (the conjugation of Apg12p and the modification of a soluble form
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