一般描述
脑提取物具有高含量的脂质,尤其是多不饱和脂肪酸(PUFA)。黑质和纹状体的提取物中铁含量很高。
应用
牛脑的脑提取物已被用于:
- 在脂质结合试验中用于制备小的单层囊泡
- 在脂质体和蛋白质自聚集测定中,有助于磷酸肌醇的回收,并终止磷脂酰肌醇5-磷酸(PtdIns5P)和PtdIns4P检测的反应
生化/生理作用
脑脂质可参与细胞信号转导、膜组织、运输蛋白修饰、相互作用和能量存储。
包装
密封安瓿瓶。
其他说明
包含磷脂酰肌醇、磷脂酰丝氨酸和其他脑脂质。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Structural and dynamic changes in human annexin VI induced by a phosphorylation-mimicking mutation, T356D
Freye-MC, et al.
Biochemistry, 42(3), 620-630 (2003)
Lipid binding regulates synaptic targeting of PICK1, AMPA receptor trafficking, and synaptic plasticity
Jin W, et al.
The Journal of Neuroscience, 26, 2380-2390 (2006)
Measurement of phosphoinositides in the zebrafish Danio rerio
Jones DR, et al.
Nature Protocols, 8(6), 1058-1058 (2013)
Qing Lu et al.
Molecular biology of the cell, 22(22), 4268-4278 (2011-10-04)
Myosin X (MyoX) is an unconventional myosin that is known to induce the formation and elongation of filopodia in many cell types. MyoX-induced filopodial induction requires the three PH domains in its tail region, although with unknown underlying molecular mechanisms.
Cholesterol and Fat Metabolism in Alzheimer?s Disease
Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders, 161-193 (2017)
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