biological source
bovine brain
type
Type I
form
powder
lipid type
phosphoglycerides
storage temp.
−20°C
Quality Level
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General description
脑提取物具有高含量的脂质，尤其是多不饱和脂肪酸（PUFA）。黑质和纹状体的提取物中铁含量很高。
Application
牛脑的脑提取物已被用于：
- 在脂质结合试验中用于制备小的单层囊泡
- 在脂质体和蛋白质自聚集测定中，有助于磷酸肌醇的回收，并终止磷脂酰肌醇5-磷酸（PtdIns5P）和PtdIns4P检测的反应
Biochem/physiol Actions
脑脂质可参与细胞信号转导、膜组织、运输蛋白修饰、相互作用和能量存储。
Packaging
密封安瓿瓶。
Other Notes
包含磷脂酰肌醇、磷脂酰丝氨酸和其他脑脂质。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Qing Lu et al.
Molecular biology of the cell, 22(22), 4268-4278 (2011-10-04)
Myosin X (MyoX) is an unconventional myosin that is known to induce the formation and elongation of filopodia in many cell types. MyoX-induced filopodial induction requires the three PH domains in its tail region, although with unknown underlying molecular mechanisms.
Measurement of phosphoinositides in the zebrafish Danio rerio
Jones DR, et al.
Nature Protocols, 8(6), 1058-1058 (2013)
Lipid binding regulates synaptic targeting of PICK1, AMPA receptor trafficking, and synaptic plasticity
Jin W, et al.
The Journal of Neuroscience, 26, 2380-2390 (2006)
Cholesterol and Fat Metabolism in Alzheimer?s Disease
Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders, 161-193 (2017)
Structural and dynamic changes in human annexin VI induced by a phosphorylation-mimicking mutation, T356D
Freye-MC, et al.
Biochemistry, 42(3), 620-630 (2003)
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