单克隆抗 人 IgG2

Monoclonal Anti-Human IgG2 (mouse IgG1 isotype) is derived from the hybridoma (HP-60141 ) produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse. IgG is the most abundant serum immunoglobulins of the immune system. IgG2 is a subtype of IgG. IgG is secreted by B cells and is found in blood and extracellular fluids.

Monoclonal Anti-Human IgG2−Biotin antibody produced in mouse has been used in indirect enzyme linked immunosorbent assay (ELISA) and immunoblot.

Low IgG2 levels were found in patients with systemic lupus erythematosus (SLE) and juvenile diabetes melitus.

该抗体对人 IgG2 具有特异性，与其他 IgG 亚类不反应。该克隆已被 IUIS/WHO 研究挑选出为应用最广泛的 IgG2 特异性单克隆抗体。

IgG provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide

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