C0662
6-羧基荧光素
~97% purity (HPLC), powder
别名:
6-FAM, 氟
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关于此项目
经验公式（希尔记法）:
C21H12O7
化学文摘社编号:
分子量:
376.32
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
MDL number:
Beilstein/REAXYS Number:
54341
产品名称
6-羧基荧光素, ≥96% (HPLC)
InChI
1S/C21H12O7/c22-11-2-5-14-17(8-11)27-18-9-12(23)3-6-15(18)21(14)16-7-10(19(24)25)1-4-13(16)20(26)28-21/h1-9,22-23H,(H,24,25)
SMILES string
OC(=O)c1ccc2C(=O)OC3(c4ccc(O)cc4Oc5cc(O)ccc35)c2c1
InChI key
BZTDTCNHAFUJOG-UHFFFAOYSA-N
assay
≥96% (HPLC)
form
powder
technique(s)
titration: suitable
color
dark yellow to dark orange
mp
>300 °C (lit.)
solubility
0.1 M NaOH: 9.80-10.20 mg/mL, clear to slightly hazy, orange
λmax
492 nm at 0.1 N in NaOH
fluorescence
λex 492 nm; λem 517 nm (pH 8.0)
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
2-8°C
Quality Level
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Application
6-羧基荧光素已用于精子细胞质膜完整性的检测。
荧光染料。
Biochem/physiol Actions
6-羧基荧光素二乙酸酯是一种膜渗透性化合物。可被细胞内酯酶水解，形成膜不可渗透的亮绿色荧光分子 6-羧基荧光素。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Bikash Malla et al.
Food and environmental virology, 11(3), 274-287 (2019-05-16)
Monitoring of environmental water is crucial to protecting humans and animals from possible health risks. Although numerous human-specific viral markers have been designed to track the presence of human fecal contamination in water, they lack adequate sensitivity and specificity in
Przemysław Płociński et al.
Nature communications, 8(1), 1251-1251 (2017-11-02)
Prokaryotic Ligase D is a conserved DNA repair apparatus processing DNA double-strand breaks in stationary phase. An orthologous Ligase C (LigC) complex also co-exists in many bacterial species but its function is unknown. Here we show that the LigC complex
Andrew B Janowski et al.
mBio, 10(4) (2019-07-11)
Recent advances in unbiased pathogen discovery have implicated astroviruses as pathogens of the central nervous system (CNS) of mammals, including humans. However, the capacity of astroviruses to be cultured in CNS-derived cells in vitro has not been reported to date.
Evgeny A Semchenko et al.
mBio, 10(4) (2019-07-11)
Neisseria gonorrhoeae is a significant threat to global health for which a vaccine and novel treatment options are urgently needed. Glycans expressed by human cells are commonly targeted by pathogens to facilitate interactions with the host, and thus characterization of
Inhong Kim et al.
Polymers, 11(7) (2019-07-25)
We recently implemented highly sensitive detection systems for photo-sensitizing potassium ions (K+) based on two-step Förster resonance energy transfer (FRET). As a successive study for quantitative understanding of energy transfer processes in terms of the exciton population, we investigated the
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