biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
ascites fluid
antibody product type
primary antibodies
clone
GC-4, monoclonal
contains
15 mM sodium azide
species reactivity
chicken, mouse, human, rabbit, rat
technique(s)
electron microscopy: suitable, immunohistochemistry (frozen sections): 1:100 using chicken cardiac muscle, microarray: suitable, western blot: 1:100 using chicken or rat cardiac muscle
UniProt accession no.
application(s)
research pathology
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... CDH2(1000)
mouse ... Cdh2(12558)
rat ... Cdh2(83501)
General description
N-钙粘蛋白是一种钙依赖性细胞粘附分子,主要存在于癌细胞中。单克隆抗-N-钙黏蛋白抗体与脂肪细胞粘附分子(ACAM)胞外域的 N 端发生反应。
Immunogen
亲和纯化的鸡心 A-CAM。
Application
单克隆抗 N-钙黏蛋白抗体可用于免疫组化(1:100),以及作为蛋白质印迹的一抗(1:1000)。
单克隆抗 N-钙黏蛋白抗体可用于免疫荧光显微镜、电子显微镜和免疫印迹,研究细胞间粘附分子的受体定位。它也可以用于研究组织中粘附和相互作用的机制。
Biochem/physiol Actions
N-钙黏蛋白调节 Src 激酶途径,还促进细胞运动和侵袭。它抑制粘附连接形成,并破坏培养的晶状体细胞的已有的连接。
单克隆抗 N-钙粘蛋白抗体与人、小鼠、兔、鸡和大鼠中的 A-CAM 分子特异性反应。
Physical form
小鼠单克隆抗 N-钙黏蛋白抗体以含有 15mM 叠氮化钠的腹水液形式提供。
Preparation Note
需要连续使用时,可在 2-8℃ 下储存一个月。对于更长期的储存,溶液可以冷冻成工作等分试样。不建议重复冷冻和解冻。如果长期储存时出现轻微混浊,使用前通过离心澄清。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
动物来源生物产品
常规特殊物品
此项目有
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全球贸易项目编号
| 货号 | GTIN |
|---|---|
| C2542-100UL | 04061835503827 |
| C2542-.2ML | 04061837873126 |