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文件

C3646

Sigma-Aldrich

壳聚糖

from shrimp shells, ≥75% (deacetylated)

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别名:
聚（D-氨基葡萄糖）, 脱乙酰几丁质
CAS号:
9012-76-4
MDL编号:
MFCD00161512
NACRES:
NA.25

生物来源

shrimp shells

质量水平

200

检测方案

≥75% (deacetylated)

形式

powder or flakes

颜色

white to beige

mp

102.5  °C ((216.5 °F ))

溶解性

acetic acid: water: 10 mg/mL, slightly hazy to hazy (with extensive sonication)
H2O: insoluble
organic solvents: insoluble

堆积密度

0.15‑0.3 g/cm3

储存温度

room temp

InChI

1S/C56H103N9O39/c1-87-56(86)65-28-38(84)46(19(10-74)96-55(28)104-45-18(9-73)95-49(27(64)37(45)83)97-39-12(3-67)88-47(85)20(57)31(39)77)103-54-26(63)36(82)44(17(8-72)94-54)102-53-25(62)35(81)43(16(7-71)93-53)101-52-24(61)34(80)42(15(6-70)92-52)100-51-23(60)33(79)41(14(5-69)91-51)99-50-22(59)32(78)40(13(4-68)90-50)98-48-21(58)30(76)29(75)11(2-66)89-48/h11-55,66-85H,2-10,57-64H2,1H3,(H,65,86)/t11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48+,49+,50+,51+,52+,53+,54+,55+/m1/s1

InChI key

FLASNYPZGWUPSU-SICDJOISSA-N

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相关类别

应用

与多价阴离子形成凝胶。 产生透明溶液，干燥后形成坚固、透明的薄膜。
虾壳衍生的壳聚糖、脱乙酰几丁质（聚β-1,4-D-葡糖胺）可用作生物相容、抗菌和环境友好的聚电解质生物材料，其具有多种应用，包括用于水处理、色谱法、化妆品添加剂、抗微生物活性的纺织品处理、纺织品的新型纤维、照相纸、可生物降解的薄膜、生物医学装置、以及用于药物递送中控制释放的微胶囊植入物。它可以通过衍生化以进一步扩展其用途。

特点和优势

生物相容、抗菌和环保的聚电解质，其具有多种应用，包括水处理、色谱法、化妆品添加剂、抗微生物活性的纺织品处理、纺织品的新型纤维、照相纸、可生物降解的薄膜、生物医学装置、以及用于药物递送中控制释放的微胶囊植入物。

质量

可能含有杂质。

制备说明

通过从虾（Pandalus borealis）壳中获得的几丁质，经过碱性脱乙酰化制备得到。在工业上，甲壳素是通过压碎虾壳，然后用酸将固体进行洗涤以除去无机和蛋白类物质而进行制造的。再通过强碱（如氢氧化钠）的处理，将纯化的几丁质脱乙酰化成壳聚糖。所得的壳聚糖可以通过在酸中溶解，然后中和和沉淀来进一步纯化。

分析说明

乙酰化程度可以通过与染料结合 或滴定的方法来确定。

其他说明

为了全面了解我们针对客户研究提供的各种多糖产品，建议您访问我们的碳水化合物分类页面。

储存分类代码

11 - Combustible Solids

WGK

nwg

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

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  3. How do I find price and availability?

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  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. What is the molecular weight of Product C3646, Chitosan from shrimp shells?

    Sigma-Aldrich has not determined an average molecular weight or a molecular weight range for this product.

  6. Is Product C3646, Chitosan from shrimp shells, USP grade?

    No, this product is not considered USP grade.  

  7. What is the pKa of Product C3646, Chitosan from shrimp shells?

    The amino group in chitosan has a pKa value of ~6.5.

  8. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Mei-Hwa Lee et al.
Materials today. Bio, 9, 100091-100091 (2021-02-02)
Induced pluripotent stem cells are usually derived by reprogramming transcription factors (OSKM), such as octamer-binding transcription factor 4 (OCT4), (sex determining region Y)-box 2 (SOX2), Krüppel-like factor 4 (KLF4), and cellular proto-oncogene (c-Myc). However, the genomic integration of transcription factors
Sirong Tan et al.
Journal of agricultural and food chemistry, 62(8), 1866-1874 (2014-02-01)
Chitosan (CTS) and capsaicin (CAP) are two kinds of effective ingredients for antiobesity, which are extracted from crab shells and Capsicum annuum. However, the strong taste of CAP makes it difficult to consume, and the antiobesity ability of CTS is
Frederik T Larsen et al.
Vaccines, 8(2) (2020-05-21)
Infectious bronchitis virus (IBV) is a highly contagious avian coronavirus. IBV causes substantial worldwide economic losses in the poultry industry. Vaccination with live-attenuated viral vaccines, therefore, are of critical importance. Live-attenuated viral vaccines, however, exhibit the potential for reversion to
Wen-Chu Hsiao et al.
Journal of the Formosan Medical Association = Taiwan yi zhi, 118(1 Pt 1), 152-161 (2018-03-04)
Cell behaviors in three-dimensional spheroids are known to be different from those in monolayer cultures; however, very few studies have compared the characteristics of cell spheroids formed through different biomaterial-induced processes. This study investigated the mechanism of melanocyte spheroid formation
Colorimetric determination of chitosan.
R A Muzzarelli
Analytical biochemistry, 260(2), 255-257 (1998-07-11)
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