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Merck
CN

C3646

壳聚糖

from shrimp shells, ≥75% (deacetylated)

别名:

聚(D-氨基葡萄糖), 脱乙酰几丁质

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关于此项目

化学文摘社编号:
UNSPSC Code:
12352201
NACRES:
NA.25
MDL number:
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biological source

shrimp shells

Quality Level

assay

≥75% (deacetylated)

form

powder or flakes

color

white to beige

mp

102.5  °C ((216.5 °F ))

solubility

acetic acid: water: 10 mg/mL, slightly hazy to hazy (with extensive sonication), H2O: insoluble, organic solvents: insoluble

bulk density

0.15‑0.3 g/cm3

application(s)

advanced drug delivery

storage temp.

room temp

SMILES string

N([C@H]1[C@@H](O[C@@H]([C@H]([C@@H]1O)O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4N)O)O[C@@H]5O[C@@H]([C@H]([C@@H]([C@H]5N)O)O[C@@H]6O[C@@H]([C@H]([C@@H]([C@H]6N)O)O[C@@H]7O[C@@H]([C@H]([C@@H]([C@H]7N)O)O[C@@H]8O[C@@H]([C@H]([C@@H]([C@H]8N)O)O[C@@H]9O[C@@H]([C@H](

InChI

1S/C56H103N9O39/c1-87-56(86)65-28-38(84)46(19(10-74)96-55(28)104-45-18(9-73)95-49(27(64)37(45)83)97-39-12(3-67)88-47(85)20(57)31(39)77)103-54-26(63)36(82)44(17(8-72)94-54)102-53-25(62)35(81)43(16(7-71)93-53)101-52-24(61)34(80)42(15(6-70)92-52)100-51-23(60)33(79)41(14(5-69)91-51)99-50-22(59)32(78)40(13(4-68)90-50)98-48-21(58)30(76)29(75)11(2-66)89-48/h11-55,66-85H,2-10,57-64H2,1H3,(H,65,86)/t11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48+,49+,50+,51+,52+,53+,54+,55+/m1/s1

InChI key

FLASNYPZGWUPSU-SICDJOISSA-N

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Application

与多价阴离子形成凝胶。 产生透明溶液,干燥后形成坚固、透明的薄膜。
虾壳衍生的壳聚糖、脱乙酰几丁质(聚β-1,4-D-葡糖胺)可用作生物相容、抗菌和环境友好的聚电解质生物材料,其具有多种应用,包括用于水处理、色谱法、化妆品添加剂、抗微生物活性的纺织品处理、纺织品的新型纤维、照相纸、可生物降解的薄膜、生物医学装置、以及用于药物递送中控制释放的微胶囊植入物。它可以通过衍生化以进一步扩展其用途。

Features and Benefits

生物相容、抗菌和环保的聚电解质,其具有多种应用,包括水处理、色谱法、化妆品添加剂、抗微生物活性的纺织品处理、纺织品的新型纤维、照相纸、可生物降解的薄膜、生物医学装置、以及用于药物递送中控制释放的微胶囊植入物。
生物相容性、抗菌和环保的聚电解质。

Preparation Note

通过从虾(Pandalus borealis)壳中获得的几丁质,经过碱性脱乙酰化制备得到。在工业上,甲壳素是通过压碎虾壳,然后用酸将固体进行洗涤以除去无机和蛋白类物质而进行制造的。再通过强碱(如氢氧化钠)的处理,将纯化的几丁质脱乙酰化成壳聚糖。所得的壳聚糖可以通过在酸中溶解,然后中和和沉淀来进一步纯化。

Analysis Note

乙酰化程度可以通过与染料结合 或滴定的方法来确定。
可能含有杂质。

Other Notes

为了全面了解我们针对客户研究提供的各种多糖产品,建议您访问我们的碳水化合物分类页面。

存储类别

11 - Combustible Solids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Sirong Tan et al.
Journal of agricultural and food chemistry, 62(8), 1866-1874 (2014-02-01)
Chitosan (CTS) and capsaicin (CAP) are two kinds of effective ingredients for antiobesity, which are extracted from crab shells and Capsicum annuum. However, the strong taste of CAP makes it difficult to consume, and the antiobesity ability of CTS is
Frederik T Larsen et al.
Vaccines, 8(2) (2020-05-21)
Infectious bronchitis virus (IBV) is a highly contagious avian coronavirus. IBV causes substantial worldwide economic losses in the poultry industry. Vaccination with live-attenuated viral vaccines, therefore, are of critical importance. Live-attenuated viral vaccines, however, exhibit the potential for reversion to
Wen-Chu Hsiao et al.
Journal of the Formosan Medical Association = Taiwan yi zhi, 118(1 Pt 1), 152-161 (2018-03-04)
Cell behaviors in three-dimensional spheroids are known to be different from those in monolayer cultures; however, very few studies have compared the characteristics of cell spheroids formed through different biomaterial-induced processes. This study investigated the mechanism of melanocyte spheroid formation
Determination of the degree of acetylation of chitin and chitosan.
Davies, D. H., and Hayes, E. R.
Methods in Enzymology, 161-pt. B, 442-446 (1988)
Sheng-Tien Li et al.
American journal of rhinology & allergy, 31(5), 289-292 (2017-09-02)
Olfactory dysfunction significantly influences patients' quality of life. Chitosan has been reported to support neuron and Schwann cell growth and even leads to orient axonal growth. However, researchers have yet to explore whether chitosan solution can promote differentiation of olfactory

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全球贸易项目编号

货号GTIN
C3646-500G04061833486122
C3646-10G04061833486108
C3646-100G04061835366415
C3646-25G04061833486115

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