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Merck
CN

C5132

咔唑

≥95% purity (GC), powder

别名:

二苯并吡咯; 二苯基吡咯

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关于此项目

经验公式(希尔记法):
C12H9N
化学文摘社编号:
分子量:
167.21
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
201-696-0
MDL number:
Beilstein/REAXYS Number:
3956
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产品名称

咔唑, ≥95% (GC)

InChI

1S/C12H9N/c1-3-7-11-9(5-1)10-6-2-4-8-12(10)13-11/h1-8,13H

InChI key

UJOBWOGCFQCDNV-UHFFFAOYSA-N

SMILES string

c1ccc2c(c1)[nH]c3ccccc23

vapor pressure

400 mmHg ( 323 °C)

assay

≥95% (GC)

form

powder

technique(s)

titration: suitable

color

white to tan

bp

355 °C (lit.)

mp

243-246 °C (lit.)

solubility

acetone: 50 mg/mL

density

1.1 g/cm3 at 18 °C

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

Quality Level

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Analysis Note

其可能含有黑色颗粒物。

Application

咔唑已用于糖醛酸的测定。

Biochem/physiol Actions

咔唑主要与 DNA 相互作用并对其造成损伤。这些事件可抑制新 DNA 或 RNA 的合成。咔唑衍生物具有抗微生物、抗肿瘤、抗癫痫、抗组胺、抗氧化、抗炎、抗腹泻、镇痛、神经保护和胰脂肪酶抑制活性。

General description

咔唑是一种芳香族杂环有机分子。

pictograms

Health hazard

signalword

Warning

Hazard Classifications

Aquatic Chronic 4 - Carc. 2 - Muta. 2

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

428.0 °F - closed cup

flash_point_c

220.0 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

危险化学品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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CARBAZOLE DERIVATIVES IN CANCER TREATMENT-A REVIEW.
Kanneti Naga M, et al.
World Journal of Pharmacy and Pharmaceutical Sciences (2015)
A complete set of hyaluronan fragments obtained from hydrolysis catalyzed by hyaluronidase: Application to studies of hyaluronan mass distribution by simple HPLC devices.
Tranchepain F, et al.
Analytical Biochemistry, 348, 232-242 (2006)
Xiaofeng Liu et al.
Advanced materials (Deerfield Beach, Fla.), 24(33), 4505-4510 (2012-06-22)
An arylated-carbazole conjugated polymer with a deep HOMO level has been developed. Solar cells based on blends of PCX3 and PC(71) BM show efficiency of 3.9% with a V(oc) of 0.96 V. The device performance can be improved to 5.1%
Jae-Min Suk et al.
Organic letters, 14(19), 5018-5021 (2012-09-18)
Chiral organic anions such as camphorsulfonates and cAMP give rise to the preferential formation of a one-handed helix of an indolocarbazole foldamer, thus inducing characteristic circular dichroic (CD) signals. Moreover, the on and off switching of the chiroptical signal can
Guodong Ji et al.
Journal of hazardous materials, 225-226, 1-7 (2012-05-23)
We examined the effects of power and treatment time on the ultrasonically enhanced ozonation of carbazole dissolved in APG(1214) surfactant solutions, including an analysis of the mechanism of OH radical formation, the zeta potential of the colloidal suspension, the influence

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