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Merck
CN

D1068

DCB

≥98% (HPLC), solid

别名:

3,3′-二氯苯甲嗪, NSC 67224

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关于此项目

经验公式(希尔记法):
C14H10Cl2N2
化学文摘社编号:
分子量:
277.15
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
Quality level:
Storage condition:
desiccated
under inert gas
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产品名称

DCB, ≥98% (HPLC), solid

InChI

1S/C14H10Cl2N2/c15-13-5-1-3-11(7-13)9-17-18-10-12-4-2-6-14(16)8-12/h1-10H/b17-9+,18-10+

SMILES string

Clc1cccc(\C=N\N=C\c2cccc(Cl)c2)c1

InChI key

XMOVWXSCYLINBJ-BEQMOXJMSA-N

assay

≥98% (HPLC)

form

solid

storage condition

desiccated
under inert gas

color

yellow

solubility

DMSO: ~6.8 mg/mL
H2O: insoluble

storage temp.

2-8°C

Quality Level

Biochem/physiol Actions

3,3′-二氯苯甲醛嗪(DCB)可用作具有中性协同作用的变构配体。在3,3′-二氟苯甲醛嗪(DFB)的帮助下,它可以阻断mGluRs(代谢型谷氨酸受体亚型5(mGluR5))的正向别构调节作用,以及3,3′-二甲氧基苯甲醛嗪(DMeOB)的负调节作用。
代谢型谷氨酸受体mGluR5的中性别构调节剂。

Features and Benefits

该化合物是《受体分类及信号转导》手册上谷氨酸受体(G蛋白家族)页面上的特色化合物。想要浏览手册的其他页面, 请单击此处

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


历史批次信息供参考:

分析证书(COA)

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