D1156
N , N -二甲基甘氨酸
≥99%, suitable for ligand binding assays
别名:
（二甲氨基）乙酸
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关于此项目
线性分子式:
(CH3)2NCH2COOH
化学文摘社编号:
分子量:
103.12
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
214-267-8
MDL number:
Beilstein/REAXYS Number:
1700261
产品名称
N , N -二甲基甘氨酸, ≥99%
InChI
1S/C4H9NO2/c1-5(2)3-4(6)7/h3H2,1-2H3,(H,6,7)
InChI key
FFDGPVCHZBVARC-UHFFFAOYSA-N
SMILES string
CN(C)CC(O)=O
assay
≥99%
form
powder
technique(s)
ligand binding assay: suitable
color
white to off-white
mp
178-182 °C (lit.)
application(s)
peptide synthesis
Quality Level
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Biochem/physiol Actions
N,N-二甲基甘氨酸 (DMG) 是一种天然 N-甲基化甘氨酸，用于与其他 N-甲基化甘氨酸（如肌氨酸和 β信息。N，N-二甲基甘氨酸用于开发基于甘氨酸的离子液体和乳化剂。N,N-二甲基甘氨酸作为 COPD 患者蛋白质降解的生物标志物可能有用。DMG 被用作识别、区分和表征氨基酸甲基转移酶的底物。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Baljit K Ubhi et al.
The European respiratory journal, 40(2), 345-355 (2011-12-21)
There is a paucity of biomarkers for chronic obstructive pulmonary disease (COPD). Metabolomics were applied to a defined COPD patient cohort from the ECLIPSE study (Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points). Results were correlated with accepted biomarkers
B A Binzak et al.
American journal of human genetics, 68(4), 839-847 (2001-03-07)
Dimethylglycine dehydrogenase (DMGDH) (E.C. number 1.5.99.2) is a mitochondrial matrix enzyme involved in the metabolism of choline, converting dimethylglycine to sarcosine. Sarcosine is then transformed to glycine by sarcosine dehydrogenase (E.C. number 1.5.99.1). Both enzymes use flavin adenine dinucleotide and
Jian Yan et al.
The American journal of clinical nutrition, 95(5), 1060-1071 (2012-03-16)
In 1998 choline Adequate Intakes of 425 and 450 mg/d were established for nonpregnant and pregnant women, respectively. However, to our knowledge, no dose-response studies have been conducted to evaluate the effects of pregnancy or maternal choline intake on biomarkers
Sheila M Innis et al.
The American journal of clinical nutrition, 93(3), 564-568 (2011-01-14)
Choline is an important constituent of acetylcholine. Choline is needed for acetylcholine in the nonneuronal acetylcholine system that includes epithelial cells of the lung and intestine, endothelial cells, and immune cells. Plasma free choline concentrations are low in children with
D Vanhauteghem et al.
Amino acids, 43(1), 245-253 (2011-09-14)
The current study first investigates the emulsifying potential of glycine and its N-methylated derivatives N-methylglycine (sarcosine), N,N-dimethylglycine (DMG) and N,N,N-trimethylglycine (betaine) under varying pH conditions. Subsequently, the effect of these test compounds on the membrane integrity of enterotoxigenic Escherichia coli
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